Boil-off gas (BOG) disposal in liquefied natural gas (LNG) tankers has long been considered inevitable owing to the constant vaporization of the LNG in the storage tanks, but results in energy waste and environmental pollution. To address these challenges, we developed a re-liquification system that can condense the BOG and return it to the storage tank. The re-liquification system was modeled, and a case study was conducted to evaluate the viability of the system. The energy waste, which was quantified by tonnes of oil equivalent (TOE), greenhouse-gas emissions in tonnes of carbon dioxide (TCO2), and cost reduction in millions of U.S. dollars (MUSD), was evaluated for five different tanker cruising speeds. The re-liquification system significantly reduced the average TOE, TCO2, and cost by up to 9120.40 TOE/year, 19,474.33 TCO2/year, and 1.9765 MUSD/year, respectively, for five different tanker speeds with multi-stage compression.