This review presents an in-depth examination of the advancements, current state, and future trends of separation and release devices in aeronautical and astronautical systems, focusing on their classification into one-point and linear devices as well as the move from pyrotechnic to nonexplosive methods. For one-point separation devices, this review discusses the evolution from traditional explosive bolts, which use high explosives to operate, to nonexplosive actuators such as shape memory alloy devices that offer resettable, low-shock options. It also highlights devices that rely on pyrotechnic initiators without using high explosives as key developments for reducing shock and increasing safety. In the section on linear separation devices, the review examines flexible linear shaped charges and mild-detonating fuses, which are crucial for precise separations such as stage and fairing detachments. Introducing expanding tubes as a new method to avoid the usual debris and damage from pyrotechnics is a big improvement. In addition, the use of clamp-band joint systems for satellite separation, secured by either pyrotechnic bolts or nonexplosive dual-initiator devices, is a common approach. The recent focus on developing pneumatic linear separation devices marks a shift toward systems that can be reused and reduce shock without explosives. Moreover, the emergence of nonexplosive satellite separation systems represents a shift toward safer and more adaptable deployment technologies. These fully mechanical actuation methods facilitate shock-free separations, which are crucial for the integrity of sensitive payloads. This review suggests that continuous innovation in nonexplosive separation technology will significantly change mission planning and system design in the aeronautics and astronautics fields.