“…Also, the Cochrane Collaboration reviews did not provide results that indicate that insulin analogues present relevant advantages in comparison with human insulin. They showed that the scientific debate on the use of insulin analogues in relation to human insulin, is still controversial 9,10 . Even with the lack of evidence on the therapeutic advantages of the insulin analogues in relation to human insulin and despite the fact they are not included in Rename, doctors continue prescribing them to their patients and they have been appealing to the courts so that the state provides these medications.…”