Rationale: Increasing physical activity is a key therapeutic aim in chronic obstructive pulmonary disease (COPD). Pulmonary rehabilitation (PR) improves exercise capacity, but there is conflicting evidence regarding its ability to improve physical activity levels.Objectives: To determine whether using pedometers as an adjunct to PR can enhance time spent in at least moderate-intensity physical activity (time expending >3 metabolic equivalents [METs]) by people with COPD.Methods: In this single-blind randomized controlled trial, participants were assigned 1:1 to receive a control intervention (PR comprising 8 wk, two supervised sessions per week) or the trial intervention (PR plus pedometer-directed step targets, reviewed weekly for 8 wk). In the randomization process, we used minimization to balance groups for age, sex, FEV 1 percent predicted, and baseline exercise capacity and physical activity levels. Outcome assessors and PR therapists were blinded to group allocation. The primary analysis was based on the intention-to-treat principle. Conclusions: Pedometer-directed step-count targets during an outpatient PR program did not enhance moderate-intensity physical activity levels in people with COPD.
Clinical trial registered with www.clinicaltrials.gov (NCT01719822).Keywords: physical activity; rehabilitation; chronic obstructive pulmonary disease Increasing physical activity levels is a key therapeutic aim in chronic obstructive pulmonary disease (COPD) (1) because physical inactivity is associated with increased risk of mortality and exacerbations, greater decline in lung function, and impaired quality of life (2-4). There is strong evidence for the effectiveness of pulmonary rehabilitation (PR) in improving exercise capacity in COPD (5), but the effect of PR on physical activity levels is modest (6).Pedometers may help people to become more active. Authors of a metaanalysis of 18 observational studies and 8 randomized