Short- and Long-Term Outcomes after Hepatic Resection for Hepatocellular Carcinoma with Concomitant Esophageal Varices in Patients with Cirrhosis

Abstract

Short- and long-term outcomes of hepatic resection in HCC patients with and without EV are similar. Limited hepatic resection for early-stage tumor is an option for Child-Pugh class A or B patients with EV.

Diagnostic value of glypican-3 in alpha fetoprotein negative hepatocellular carcinoma patients

“…The prognosis of patients with HCC is generally very poor with a 5-year survival rate of less than 15% since most of them are diagnosed clinically at their late stage 2 . Therefore, early detection and diagnosis is still the key way to improve the prognosis of HCC 3 .…”

Influence of Clinically Significant Portal Hypertension on Hepatectomy for Hepatocellular Carcinoma: a Meta-analysis

“…Similarly, Imamura et al reported their experience in a series of 1056 consecutive hepatectomies without mortality and showed that presence of PHT was not a predictor for post-operative complications (Imamura et al, 2003). Kawano et al also found that patients with oesophageal varices had similar outcomes compared with those without oesophageal varices in a study of 131 patients including (Kawano et al, 2008). It is noteworthy that, instead of measuring HVPG directly, indirect criteria were used to define PHT in these studies failed to replicate those Barcelona group's findings.…”

Current advances made in the surgical treatment of hepatocellular carcinoma

“…Overall surgical results depend not only on the presence of portal hypertension but also on the residual liver function, size of segmental resection and the remnant liver volume. 25,26 Prognostic relevance of clinically significant portal hypertension after hepatic resection in patients with HCC is still a matter for debate as with improvement in anesthesia and surgical techniques, specifically laparoscopic resection, results of surgery are much superior. 27 The recent study by Santambrogio et al 28 reported that the presence of clinical portal hypertension alone does not influence the post-operative course of cirrhotic patients who undergo hepatic resection.…”