Background
Cystic echinococcosis (CE) is a zoonosis caused by cestodes of
Echinococcus granulosus
(
sensu lato
) complex. In Nigeria, reports on the prevalence of CE, although limited, have been found to vary with location and host with higher prevalence and fertility rate observed in camels than other livestock. Until now, information regarding the molecular characteristics, genetic population structure, and genotypes of
Echinococcus
is lacking. Therefore, this study was aimed at addressing these gaps in knowledge.
Methods
We describe the genetic status of 31
Echinococcus
isolates collected from slaughtered livestock (camels, cattle and goats) based on the full-length mitochondrial cytochrome c oxidase subunit 1 (
cox
1) and NADH dehydrogenase subunit 1 (
nad
1) genes.
Results
The resulting nucleotide sequences
via
the NCBI BLAST algorithm and Bayesian phylogeny of
cox
1 and
cox
1
–nad
1 genes using MrBayes v.3.1.2 showed that all isolates were clearly
E. canadensis
(G6/G7) and were 99–100% identical to previously reported G6/G7 haplotypes across Europe, Asia, North and East Africa.
Conclusions
Although, the G1 genotype is believed to be responsible for the majority of global CE burden, reports from a number of West African countries including Nigeria suggest that
E. canadensis
G6/G7 genotype could be the major causative agent of CE in the subregion. This study provides for the first time insight into the genetic population structure of
Echinococcus
species as well as implications for CE control in Nigeria.
Electronic supplementary material
The online version of this article (10.1186/s13071-019-3644-z) contains supplementary material, which is available to authorized users.