2023
DOI: 10.1113/ep090912
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Short exposure to high salt in drinking solution leads to a cardiovascular phenotype of hypertension without changes in the blood volume of rats

Abstract: New Findings What is the central question of this study? Is the cardiovascular phenotype of high blood pressure observed in rats salt loaded with 2% NaCl in drinking solution a blood volume‐dependent hypertension? What is the main finding and its importance? Animals exposed to 2% NaCl drinking solution develop hypertension, with dominance of sympathetic outflow and high [Na+] in the cerebrospinal fluid, but without changes in the blood volume. The phenotype of salt‐dependent hypertension might be related to a… Show more

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