Short-term and long-term neurocognitive outcome in on-pump versus off-pump CABG

Abstract

This study showed no short-term difference between the on-pump and off-pump CABG groups. The long-term cognitive outcome revealed more favorable results for the off-pump group. Although a preference to operate multiple vessel disease with classical cardiopulmonary bypass (CPB) has to be considered, the present study shows evidence for a different pattern of early decline and late recovery of cognitive functions in patients undergoing CABG with and without CPB.

Effects of N-acetylcysteine on neurocognitive functions after coronary artery bypass graft surgery

“…[25] Yine bizim çalışmamızda, kontrol grubunda yarıdan fazla testte ameliyat sonrası performans azalması görülmektedir. Shaw ve ark.…”

A population‐based study of the association between coronary artery bypass graft surgery (CABG) and cognitive decline: the Cache County study

“…Because CABG is a surgery that is primarily given to men, we conducted a test for independence between gender and CABG exposure using a Pearson 2 test. We assessed the nature of the significant observed association between gender and CABG exposure by examining adjusted standardized residuals (ASR) for each combination of gender category and CABG exposure level (Stroobant et al, 2002). These residuals are computed under the assumption of no association, and are approximately normally distributed.…”

Long-term Cognitive Decline in Older Subjects Was Not Attributable to Noncardiac Surgery or Major Illness

“…3,13,14 Lasting cognitive decline has been found in more than 40% of patients up to five years after cardiac surgery 15 , but the use of cardiopulmonary bypass may independently contribute to this cognitive decline. 16,17 The possible lack of lasting cognitive decline following non-cardiac surgery has fueled a controversy surrounding the clinical significance and even the existence of POCD as a distinct phenomenon. 14,18 Interestingly, cognitive decline has also been described with both acute and chronic illness.…”