Short-term binge drinking, marijuana, and recreational drug use trajectories in a prospective cohort of people living with HIV at the start of COVID-19 mitigation efforts in the United States

Meanley, Steven; Choi, Seul Ki; Thompson, Azure B.; Meyers, Jacquelyn L.; D’Souza, Gypsyamber; Adimora, Adaora A.; Mimiaga, Matthew J.; Kempf, Mirjam-Colette; Konkle‐Parker, Deborah; Cohen, Mardge H.; Teplin, Linda A.; Murchison, Lynn; Rubin, Leah H.; Rubtsova, Anna; Weiss, Deborah Jones; Aouizerat, Brad; Friedman, M. Reuel; Plankey, Michael; Wilson, Tracey E.

doi:10.1016/j.drugalcdep.2021.109233

Cited by 12 publications

(11 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of those, 283 were removed after initial screening due to duplication, and 727 articles were excluded based on screening titles and abstracts. The remaining 78 full‐text articles were assessed for eligibility, and 45 studies met the inclusion criteria and were, therefore, included in the final review and data extraction [19–63]. See Figure 1 for the PRISMA flowchart of the study selection and rationales for the exclusion of full‐text articles.…”

Section: Resultsmentioning

confidence: 99%

The impact of the COVID‐19 pandemic on mental health, associated factors and coping strategies in people living with HIV: a scoping review

Hong¹,

Queiroz

Hoskin³

2023

J Int AIDS Soc.

View full text Add to dashboard Cite

Introduction:The COVID-19 pandemic and associated measures implemented by authorities have created additional stressors and increased the risk of psychological illnesses among people living with HIV (PLWH). Yet, there is no collective evidence on the mental health status of this population during the global pandemic and associated factors. This scoping review aimed to synthesize the evidence in the current literature related to the mental health outcomes and challenges faced by PLWH during the COVID-19 pandemic, identify the associated factors with psychological distress and summarize various coping strategies to ease these psychological distresses used by this population. Methods: We conducted a scoping review following the PRISMA-ScR guideline and a literature search in four electronic databases in August 2022. Three reviewers independently screened all the search records and extracted the data from studies that met the inclusion criteria. Factors associated with worsened mental health outcomes were synthesized according to the socio-ecological framework. Results: Among 1100 research records, 45 articles met the eligibility criteria and were included in the final review and data extraction, most of which were quantitative analyses. PLWH reported high rates of mental health problems during the pandemic. Multi-level factors were associated with increased psychological distress, including substance use, antiretroviral adherence, social support, financial hardship and economic vulnerability during the pandemic. PLWH used social media as a coping strategy to foster social support to deal with growing mental distress. Increased mental health illnesses were associated with increased substance use, it was also found associated with suboptimal medication adherence and antiretroviral therapy (ART) care engagement. Discussion: PLWH experienced high rates of mental health illnesses, such as depression during the global COVID-19 pandemic. There is an urgent need to provide comprehensive HIV treatment and mental health services as the pandemic continues to evolve. Conclusions: The review summarized how the mental health of PLWH was affected during the COVID-19 pandemic. Future work in the implementation of effective interventions to promote mental health in this population is needed, not only to ensure their quality of life but also to help them maintain ART adherence and healthcare during more unprecedented times.

show abstract

Section: Resultsmentioning

confidence: 99%

The impact of the COVID‐19 pandemic on mental health, associated factors and coping strategies in people living with HIV: a scoping review

Hong¹,

Queiroz

Hoskin³

2023

J Int AIDS Soc.

View full text Add to dashboard Cite

show abstract

“…The remaining PLWH-population investigated by reported either no change (55%) or a decrease (16.2%) of their cannabis use (Table 1). A further US-study on cannabis-using PLWH's reported no change of their cannabis consumption during the pandemic (Meanley et al 2022).…”

Section: Prospective Studiesmentioning

confidence: 96%

Cannabis use, abuse and dependence during the COVID-19 pandemic: a scoping review

et al. 2022

View full text Add to dashboard Cite

The interaction between cannabis use or addiction and SARS-COV-2 infection rates and COVID-19 outcomes is obscure. As of 08/01/2022 among 57 evaluated epidemiological/clinical studies found in Pubmed-database, most evidence for how cannabis use patterns were influenced by the pandemic was given by two systematic reviews and 17 prospective studies, mostly involving adolescents. In this age group, cannabis use patterns have not changed markedly. For adults, several cross-sectional studies reported mixed results with cannabis use having increased, decreased or remained unchanged. Two cross-sectional studies demonstrated that the severity of adults´ cannabis dependence was either increased as a consequence of increasing cannabis use during the pandemic or not changed. Regarding the effect of cannabis use on COVID-19 outcomes, we found only five retrospective/cross-sectional studies. Accordingly, (i) cannabis use did not impact mild COVID-19 symptoms; (ii) cannabis using individuals experienced more COVID-19-related hospitalizations; (iii) cannabis using veterans were associated with reduced SARS-COV-2 infection rates; (iv) frequent cannabis use was significantly associated with COVID-19 mortality, and (v) cannabis dependents were at higher risk of COVID-19 breakthrough after vaccination. It should be outlined that the validity of these retrospective/cross-sectional studies (all self-reports or register/e-health-records) is rather low. Future prospective studies on the effects of cannabis use on SARS-COV-2 infection rates and COVID-19 outcomes are clearly required for conclusive risk–benefit assessments of the role of cannabis on users’ health during the pandemic. Moreover, substance dependence (including cannabis) is associated with (often untreated) somatic comorbidity, which severity is a proven key risk factor for worse COVID-19 outcomes.

show abstract

“…Recreational drug use is an increasing non-HIVrelated comorbidity in people living with HIV [9][10][11][12][13]. The prevalence of recreational drug use has increased by around 50% among people living with HIV in recent years, particularly in men who have sex with men (MSM) [9][10][11][12][13], with data showing that almost half of MSM had used substances at some time in the previous 12 months [10]. Cannabis, followed by cocaine and amphetamines, are the main substances used by people living with HIV, with a polyconsumption pattern in more than threequarters of subjects [11].…”

Section: Introductionmentioning

confidence: 99%

“…Recreational drug use is an increasing non‐HIV‐related comorbidity in people living with HIV [9–13]. The prevalence of recreational drug use has increased by around 50% among people living with HIV in recent years, particularly in men who have sex with men (MSM) [9–13], with data showing that almost half of MSM had used substances at some time in the previous 12 months [10]. Cannabis, followed by cocaine and amphetamines, are the main substances used by people living with HIV, with a polyconsumption pattern in more than three‐quarters of subjects [11].…”

Section: Introductionmentioning

confidence: 99%

Amphetamine‐related intoxications in people living with HIV: An observational study in an emergency department in Barcelona (Spain) from 2018 to 2020

et al. 2022

View full text Add to dashboard Cite

Background: Stimulant drugs, particularly amphetamines, are more commonly implicated in drug-related deaths in people living with HIV; however, the clinical characteristics of amphetamine-related intoxication in people living with HIV are poorly described. Material and methods:We conducted a retrospective study in people living with HIV who were admitted for amphetamine-related intoxication to an emergency department of a teaching hospital between 2018 and 2021. Severe intoxication (SI) was arbitrarily defined as requiring admission to the emergency medical support unit and receiving medical treatment for ≥6 h. Results: In total, 170 male patients with a median age of 36.2 + 7.5 years were included in the study. A total of 77 (45.3%) individuals had mental disorders, and 120 (85.7%) had HIV-1 RNA suppression, with a median CD4 cell count of 696 (interquartile range 490-905). In total, 61 (37.9%) individuals were on ritonavir/cobicistat-based regimens. Presenting clinical syndromes included agitation in 60 (35.3%) subjects, anxiety in 37 (21.7%), psychosis in 27 (15.8%), chest pain in 26 (15.3%) and altered level of consciousness in 20 (11.7%). SI was observed in 48 (28.2%) individuals, 12 (7.1%) required admission to the intensive care unit, and two (1.2%) died.Altered level of consciousness (odds ratio [OR] 6.5; 95% confidence interval [CI] 2.2-18.9; p < 0.01), psychosis (OR 5.8; 95% CI 2.2-15.1; p < 0.01) and suicide attempt (OR 4.6;; p 0.01) were associated with SI in the adjusted analysis. Conclusions: Amphetamine-related intoxication causes high morbidity in people living with HIV. Healthcare providers serving these patients should consider incorporating harm-reduction measures in the prevention of amphetamine-related intoxication.

show abstract

Short-term binge drinking, marijuana, and recreational drug use trajectories in a prospective cohort of people living with HIV at the start of COVID-19 mitigation efforts in the United States

Cited by 12 publications

References 54 publications

The impact of the COVID‐19 pandemic on mental health, associated factors and coping strategies in people living with HIV: a scoping review

The impact of the COVID‐19 pandemic on mental health, associated factors and coping strategies in people living with HIV: a scoping review

Cannabis use, abuse and dependence during the COVID-19 pandemic: a scoping review

Amphetamine‐related intoxications in people living with HIV: An observational study in an emergency department in Barcelona (Spain) from 2018 to 2020

Contact Info

Product

Resources

About