Short-Term Effect of Aerobic Exercise on Symptoms in Multiple Sclerosis and Chronic Fatigue Syndrome

Aerobic exercises alleviate symptoms of fatigue related to inflammatory cytokines in obese patients with type 2 diabetes.

“…We observed reduction of markers of systemic inflammation and fatigue symptoms. The results of our study agreed with several previous studies suggesting 12-weeks aerobic exercise training program promotes the modulation of systemic inflammation and fatigue symptoms of obese patients with type 2 diabetes [27][28][29][30][31][32][33][34][35][36][37][38][39] . Rosety-Rodriguez and colleagues conducted a 12-week arm cranking exercise program for spinal cord injury patients at a moderate work intensity of 50% to 65% of heart rate reserve for of 3 sessions per week .…”

“…Rosety-Rodriguez and colleagues conducted a 12-week arm cranking exercise program for spinal cord injury patients at a moderate work intensity of 50% to 65% of heart rate reserve for of 3 sessions per week . Their results proved that arm cranking exercise improved lowgrade systemic inflammation by decreasing plasma levels of inflammatory cytokines Learmonth and colleagues conducted a pilot study to determine whether a 15-minute bout of moderate-intensity aerobic cycling exercise would affect symptoms (pain and fatigue) and function (Timed 25-Foot Walk test and Timed Up and Go test) in people with multiple sclerosis (MS) or chronic fatigue syndrome (CFS), their results suggest that people with MS or CFS may undertake 15 minutes of cycling as moderate aerobic exercise with no expected negative impact on pain, fatigue or function 31 . Sangelaji and colleagues conducted a randomized controlled clinical trial on 59 multiple sclerosis patients who received 10 weeks of combination therapy including aerobic, strengthening, balancing and stretching exercises.…”

Physical activity and exercise training in multiple sclerosis: a review and content analysis of qualitative research identifying perceived determinants and consequences

“…This is of interest as quantitative inquiry suggests that overall, exercise training significantly reduces fatigue [7]. There is limited evidence of the short-term effect of physical activity and exercise in those with MS [79] and our findings indicate the importance of addressing perceived and physiological fatigue in both its acute and chronic states. For example, focusing recruitment efforts in MS physical activity intervention to recruit participants with higher selfreported levels of fatigue [80].…”

Physiological measures in participants with chronic fatigue syndrome, multiple sclerosis and healthy controls following repeated exercise: a pilot study

“…In a study by Learmonth et al . (), subjective measures of postexertional fatigue were compared between MS and CFS populations, with findings suggesting that no differences are evident between the two (Learmonth et al ., ). Our study was the first study to compare objective, physiological responses between CFS/ME and MS. Our study found that although MS workload at RER was significantly lower than healthy controls on both days, MS participants achieved a higher workload at RER on day, opposite to the CFS/ME response.…”