Short-term estrogen replacement therapy reduces platelet marker levels in Malaysian postmenopausal women

Sheikh, Shabbir Ahmad; Roshan, Tariq; Khattak, Muhammad Naeem; Baig, Atif Amin; Noor, Shahreza Johan; Hassan, Rosline; Zaki, Nik Mohamed

doi:10.1258/mi.2011.011001

Cited by 1 publication

(1 citation statement)

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“…Although the relationships of different hypertension subtypes with age and sex are controversial, a considerable number of studies [ 5 , 33 , 35 , 29 ] agree with the view that being female and being old play pivotal roles in the development of ISH. Another study [ 42 ] from Sheikh et al showed that platelet activation decreased after hormone replacement therapy among postmenopausal women. Our data showed that the prevalence of ISH exceeded half of the population of individuals over 60 years for the first time in females, and the mean age of women with ISH was 63.15 years, which was older than the usual menopause age.…”

Section: Discussionmentioning

confidence: 99%

The different associations between platelet distribution width and hypertension subtypes in males and females

Jin

Meng

et al. 2020

Bioscience Reports

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The prevalence of hypertension has increased rapidly in recent years. Currently, increasing attention has been paid to the relationship between hypertension and platelet abnormalities. As a simple and available platelet parameter, platelet distribution width (PDW) can reflect platelet abnormalities and further reflect the risk of thrombotic diseases. However, the views on PDW and hypertension are controversial at present studies. Hence, we aimed to find the associations between PDW and hypertension subtypes in this study. 73469 participants (44665 males and 28804 females) were enrolled. We found that PDW was a risk factor for isolated systolic hypertension (ISH), and the risk of ISH increased with PDW quartiles among women. In men, high PDW might be a risk factor for isolated diastolic hypertension and systolic-diastolic hypertension.

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Section: Discussionmentioning

confidence: 99%

The different associations between platelet distribution width and hypertension subtypes in males and females

Jin

Meng

et al. 2020

Bioscience Reports

View full text Add to dashboard Cite

show abstract

Short-term estrogen replacement therapy reduces platelet marker levels in Malaysian postmenopausal women

Abstract: Short-term ERT leads to reduction in platelet activity, which might contribute to protection against cardiovascular diseases in healthy PMW.

Cited by 1 publication

References 23 publications

The different associations between platelet distribution width and hypertension subtypes in males and females

The different associations between platelet distribution width and hypertension subtypes in males and females

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