Short-term exposure to air pollution and outpatient visits for conjunctivitis: a time-series analysis in Urumqi, China

Gui, Si-Yu; Wang, Xin-Chen; Qiao, Jian-Chao; Xiao, Duncheng; Hu, Chengyang; Tao, Fangbiao; Li, Dongwei; Yi, Xiang-Long; Jiang, Zhengxuan

doi:10.1007/s11356-023-26995-2

Cited by 2 publications

(1 citation statement)

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“…Nevertheless, heightened levels of air pollution might be linked to greater instability of the tear film ( 11 , 12 ). The association between air pollution and allergic conjunctivitis has been confirmed ( 5 , 13 ). Allergic conjunctivitis, characterized by the release of numerous inflammatory mediators, leads to deficiencies in the mucus layer and instability of the tear film, making it a major contributing factor to DED ( 14 ).…”

Section: Introductionmentioning

confidence: 93%

Time-series analysis of the association between air pollution exposure and outpatient visits for dry eye disease: a case study in Zhengzhou, China

Xia,

Yang,

Sun

et al. 2024

Front. Public Health

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BackgroundDry eye disease (DED) is a prevalent ocular surface disease that significantly impacts patients’ quality of life. The association between air pollution and the risk of dry eye disease remains uncertain.MethodsData on outdoor air pollutants, meteorological information, and outpatient visits for DED were collected from July 1, 2014, to December 31, 2019. The relationship between ambient air pollutants and DED outpatient visits was analyzed using a generalized additive model with a Poisson distribution.ResultsAmong the 5,204 DED patients included in the study, 63.76% were female and 36.24% were male. The single-pollutant model revealed a significant association between a 10 μg/m3 increase in concentrations of fine-particulate matter with a median aerometric diameter of less than 10 μm (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), and carbon monoxide (CO) and outpatient visits for DED. Fine-particulate matter with a median aerometric diameter of less than 2.5 μm (PM2.5) showed a significant association with DED outpatient visits in males and the 19–59 years age group. The strongest associations between air pollutants and outpatient visits were observed in male patients and during the cold season.ConclusionThe noteworthy correlation between air pollutants and DED outpatient visits can offer evidence for policy makers and underscore the significance of reinforcing environmental protection.

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