Short-term exposure to ambient fine particulate matter (PM2,5 and PM10) and the risk of heart rhythm abnormalities and stroke

Kowalska, Małgorzata; Kocot, Krzysztof

doi:10.5604/17322693.1220389

Cited by 35 publications

(19 citation statements)

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“…Direct penetration of smallest particles to bloodstream is also important. Endothelium dysfunction and vasoconstriction are among observed effects of this process (6,(11)(12).…”

Section: Pathomechanism Of Air Pollution Impact On Healthmentioning

confidence: 99%

“…Istotna jest także bezpośrednia penetracja najdrobniejszych frakcji pyłu do krwiobiegu, a udokumentowane efekty tego procesu obejmują m. in. dysfunkcję śródbłonka i skurcz naczyń (6,(11)(12).…”

Section: Patomechanizm Oddziaływania Zanieczyszczeń Powietrzaunclassified

“…Fine particulate matter is particularly dangerous for the function of respiratory and cardiovascular system (1,5). The highest risk of negative changes is assigned to particulate matter of aerodynamic diameter of particles below 2.5 µm (PM 2,5 ) due to its smaller size which enables deeper penetration into respiratory tract and the possibility of migration to the bloodstream (5)(6).…”

Section: Introductionmentioning

confidence: 99%

“…Szczególnie niebezpieczne dla funkcjonowania układu oddechowego i układu krążenia jest narażenie na drobny pył zawieszony w powietrzu (1,5). Największe ryzyko wystąpienia niekorzystnych zmian przypisywane jest drobnemu pyłowi frakcji PM 2,5 , o średnicy aerodynamicznej cząsteczek poniżej 2,5 µm, ze względu na mniejszy rozmiar umożliwiający głębszą penetrację do układu oddechowego, a także możliwość migracji do układu krążenia (5)(6).…”

Section: Introductionunclassified

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Recreational physical activity and the problem of particulate matter air pollution

Kocot

2019

Przegl Epidemiol

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Studies reveal the negative impact of exposure to particulate air pollution on human health, especially on respiratory and circulatory systems. At the same time the beneficial effects of maintaining adequate level of physical activity are well known. In this review author presents analysis of chosen current articles about health effects of recreational physical activity in the environment of high level of ambient particulate matter air pollution. Available data suggests that there are complex relations between physical activity and exposure to air pollution. The direct positive effects of recreational physical activity include decrease of diastolic blood pressure and bronchial dilatation. It is proven that particulate air pollution show contrary impact on respiratory and cardiovascular systems. The mechanisms of this influence consist of induction of inflammation in respiratory epithelial cells, increase of oxidative stress and alterations in autonomic nervous system regulation. Changes induced by air pollution, expressed by the decrease of spirometry parameters (most commonly FEV1 decrease) were observed even in young and healthy adults doing recreational physical activity. Nevertheless, several studies suggest modulatory impact of physical exercises, which may limit the pro-inflammatory influence of particulate air pollution. Less expressed short-term negative effects of exposure have been observed in people doing physical exercise in comparison to those being inactive at the same time. In addition, apart from direct health effects, air pollution may also discourage exposed people from doing physical activity. Therefore, balanced choices regarding physical activity are needed, in order to decrease the negative impact of exposure to air pollution, without limiting the positive impact of physical activity. Still, new research is needed in order to fully explain relations between physical activity and exposure to air pollution. This will allow to elaborate physical activity guidelines including current air pollution level, better risk communication and promotion of safe ways of exercise.

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“…Direct penetration of smallest particles to bloodstream is also important. Endothelium dysfunction and vasoconstriction are among observed effects of this process (6,(11)(12).…”

Section: Pathomechanism Of Air Pollution Impact On Healthmentioning

confidence: 99%

Section: Patomechanizm Oddziaływania Zanieczyszczeń Powietrzaunclassified

Section: Introductionmentioning

confidence: 99%

Section: Introductionunclassified

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Recreational physical activity and the problem of particulate matter air pollution

Kocot

2019

Przegl Epidemiol

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“…Among important mechanisms respon-Review Article 51-57 sible for the observed health impact of particulate matter there are induction and intensification of inflammation, increased oxidative stress increased autonomic nervous system activity, vasoconstriction, rheological changes and endothelial dysfunction. Among people of higher susceptibility to fine dust negative health impact are: elderly (over 65 years old), obese people, patients with respiratory and cardiovascular diseases, patients with diabetes and those with coagulation disorders 24 . In another study of short-term exposures to ambient air pollution and risk of recurrent ischemic stroke in order to investigate the association between short-term changes in ambient pollution (particulate matter <2.5μm in aerodynamic diameter (PM2.5) and ozone (O 3 )) and the risk of recurrent ischemic stroke among individuals living in a bi-ethnic community, there were no evidence of associations between previous-day air pollution levels and recurrent ischemic stroke.…”

Section: -57mentioning

confidence: 99%

Air Pollution: a New Risk Factor for Developing Stroke

Demarin¹,

Morović²,

Đerke³

2019

Rad Hrvatske akademije znanosti i umjetnosti

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Many years scientist try to explore the connection between air pollution and its influence on human health and after numerous conducted researches they came up with the clear evidence that air pollution has a significant impact on overall health and especially on stroke. In the Global Burden of Disease Study, it has emerged as a significant contributor to the global stroke burden, especially in low-and middle-income countries. Furthermore, these and some other researches have suggested a closer link between air pollution and ischemic stroke, due to huge diversity of the results of numerous other studies, for drawing definitive conclusions, further research is still needed. Due to the complexity of stroke with its types and subtypes, the results of their reaction to air pollution differ. Some studies have shown the link between cardioembolic stroke and AP, others with SAH but not with intracerebral haemorrhage. There was a suggestion that nitrogen dioxide exposure might be associated with stroke caused by small vessel disease, while other studies are not reporting any association of AP and the risk of ischemic stroke. In some studies, AP was more affecting young adults and in some, it was more pronounced in women. Some studies reported a more clear link between AP and recent stroke in patients with other risk factors like diabetes and previous stroke. Studies have varied by the concentration and types of pollutants studied, which vary geographically, as well as by duration to AP exposure being short-or long-term, and in some studies being present only during warm seasons.Regulations have improved air quality in many countries in Europe and the United States, resulting in greater life expectancy, which highlights the continued importance of further efforts in that direction. Sažetak: Zagađenje Zraka: novootkriveni faktor riZika u raZvoju moždanog udaraVeć nekoliko godina znanstvenici pokušavaju istražiti povezanost zagađenja zraka i njegovog utjecaja na zdravlje ljudi, a nakon brojnih provedenih istraživanja došli su do jasnih dokaza da zagađenje zraka ima značajan utjecaj na cjelokupno zdravlje, s posebnim naglaskom na ravoj moždanog udara. U "Global Bourden of Disease" (szo)pokazalo se da zagađeni zrak značajno doprinosi globalnom opterećenju od moždanog udara, posebno u zemljama s niskim i srednjim dohotkom. Nadalje, ova i neka druga istraživanja sugeriraju blisku povezanost zagađenja zraka i ishemijskim moždanim udarom, dok zbog raznolikosti rezultata brojnih drugih studija, za donošenje konačnih zaključaka, potrebna su još daljnja istraživanja. Zbog složenosti moždanog udara s njegovim tipovima i podvrstama, rezultati njihove reakcije na onečišćenje zraka razlikuju se. Neke studije pokazuju vezu između kardioemboličkog moždanog udara i zagađenog zraka, druge sa subarahnoidalnim krvarenjem, ali ne i intracerebralnog krvarenjem. Bilo je nagovještaja i da je izlaganje dušičnom dioksidu povezano s moždanim udarom uzrokovanim bolešću malih žila, dok druge studije ne opisuju tu povezanost sa rizikom od ishemijskog m...

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Quantification of the Cost and Potential Environmental Effects of Unused Pharmaceutical Products in Cataract Surgery

et al. 2019

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IMPORTANCE Pharmaceutical products, including unused portions, may contribute to financial and environmental costs in the United States. Because cataract surgery is performed millions of times each year in the United States and throughout the rest of the world, understanding these financial and environmental costs associated with cataract surgery is warranted. OBJECTIVE To investigate the financial and environmental costs of unused pharmaceutical products after phacoemulsification surgery. DESIGN, SETTING, AND PARTICIPANTS This descriptive qualitative study included 4 surgical sites in the northeastern United States (a private ambulatory care center, private tertiary care center, private outpatient center, and federally run medical center for veterans). Prices and data for use of services and pharmaceuticals were obtained for the tertiary care and outpatient centers from

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Short-term exposure to ambient fine particulate matter (PM2,5 and PM10) and the risk of heart rhythm abnormalities and stroke

Cited by 35 publications

References 0 publications

Recreational physical activity and the problem of particulate matter air pollution

Recreational physical activity and the problem of particulate matter air pollution

Air Pollution: a New Risk Factor for Developing Stroke

Quantification of the Cost and Potential Environmental Effects of Unused Pharmaceutical Products in Cataract Surgery

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