Short Term Hospital Outcome of Intracerebral Hemorrhage on The Basis of Admission Serum Calcium Level

Abstract

(1) Background: Spontaneous intracerebral haemorrhage (ICH) accounts for approximately 15% of all strokes and is a leading cause of disability, with a one-month mortality rate of 40%. Whereas factors predicting short-term mortality are well known, data regarding long-term outcome are scarce and imprecise. Only a few studies revealed association of serum calcium level with outcome of stroke particularly ischaemic stroke but data regarding intracerebral hemorrhage is very limited. Therefore, to reveal the short-term hospital outcome of intracerebral hemorrhage patient on the basis of admission serum calcium level is the objective of the study. Methods: This study was a hospital based observational study and conducted at the Department of Neurology, Neurosurgery and Medicine in Dhaka Medical College Hospital. People who were suffering from intracerebral haemorrhage and were admitted in the department of Neurology, Neurosurgery and Medicine were approached for inclusion in the study according to inclusion and exclusion criteria. Ethical issues were ensured properly. After written informed consent history and physical examination were done. Diagnosis was confirmed by researcher with the aid of CT scan. Total 365 consecutive samples were collected and incompletion of data was considered exclusion of the study. Following radiological confirmation blood were drawn to measure serum calcium level with maintaining all aseptic precautions. For analysis patients’ corrected serum calcium level were divided into three tertiles: T1 = <2.20 mmol/l, T2 = 2.20 to 2.40 mmol/l and T3 = >2.40 mmol/l. The principal investigator interviewed each patient individually and in case of unconscious patient; history was collected from attendant of the patient. All these were registered, documented and analyzed in the statistical program Statistical Package for Social Science (SPSS) version 20.0. Results: Out of a total of 365 patients, Mean age of the population was 58.43(±12.33).................