Short-term intraocular tamponade with perfluorocarbon heavy liquid

Abstract

Short-term perfluoro-n-octane tamponade achieved a stable reattachment rate of 76% when used to manage challenging retinal pathologies.

Pars Plana Vitrectomy With Medium-Term Postoperative Perfluoro-N-Octane for Recurrent Inferior Retinal Detachment Complicated by Advanced Proliferative Vitreoretinopathy

“…15,28 We observed a high rate (32%) of a characteristic inflammation compared with some previous clinical studies using postoperative PFO for RD. [22][23][24] This may be because of the longer average duration of PFO used in the present study, or underrecognition and retrospective design of previous studies. Rush et al 22 have recently observed inflammation with posterior lens capsule deposits in a comparable proportion (8/39) of eyes with postoperative PFO and reported similar resolution after PFO removal and clinical management with topical corticosteroids.…”

“…Intraocular pressure elevation is a well-described phenomenon in the context of silicone oil, 30 but it has been ill-defined regarding PFO as a vitreous substitute. Some previous retrospective series [22][23][24]26 involving a similar technique have reported no or lower incidence. Rush et al 22 recently reported IOP elevation in 36% of eyes treated with postoperative PFO that was associated with macroscopically detectable PFO in the anterior chamber, identical to our report.…”

“…Previous reports have indicated mixed results using heavier-than-water compounds, and previous series investigating PFO 11,[22][23][24]27 have reported small samples of patients with PVR. The results of the present study indicate that a high rate of anatomical success can be achieved with short duration postoperative PFO in advanced PVR.…”

“…This is similar to previous reports of superior retinal pathologic assessment after postoperative highdensity vitreous substitutes. 11,23 We hypothesize that inferior tamponade agents may promote superior vitreous base countertraction and may predispose to new retinal tears in this location. Therefore, we suggest careful inspection of the peripheral retina, especially the superior vitreous base, during PFO removal and prophylactic retinopexy of any suspicious areas.…”

“…Recently, several reports have indicated that PFO may be left in the vitreous cavity postoperatively for short durations and may be useful for inferior retinal tamponade. [22][23][24] The purpose of the present study was to describe a technique involving PPV, intermediate (2-to 3-week duration) "medium-term" postoperative PFO (MT-PFO) followed by staged PFO removal in patients presenting with inferior retina redetachment complicated by Grade C PVR.…”