2021
DOI: 10.1186/s41983-020-00251-7
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Short-term outcome in ischemic stroke patients after thrombolytic therapy

Abstract: Background Stroke represents the second leading cause of death in the world after myocardial infarction. Intravenous (IV) thrombolysis with recombinant tissue plasminogen activator (alteplase, rt-PA) is the only pharmacological therapy that was approved for treatment within 4.5 h of acute ischemic stroke (AIS) onset. We aimed to predict the 3-month outcome of AIS patients who received alteplase regarding mortality, spontaneous intra-cerebral hemorrhage (sICH), and functional outcome in comparis… Show more

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Cited by 17 publications
(9 citation statements)
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“…In the subgroup analysis according to the type of stroke, there were three studies on hemorrhagic stroke [ 19 , 20 , 22 ], including 830 patients, of whom 237 developed END, and six studies on ischemic stroke [ 15 18 , 21 , 23 ], including 1894 patients, of whom 505 developed END. The NLR levels in patients with hemorrhagic stroke who developed END were similar to those without END (SMD = 0.84, CI 95% = −0.10-1.77, P value = 0.07).…”
Section: Resultsmentioning
confidence: 99%
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“…In the subgroup analysis according to the type of stroke, there were three studies on hemorrhagic stroke [ 19 , 20 , 22 ], including 830 patients, of whom 237 developed END, and six studies on ischemic stroke [ 15 18 , 21 , 23 ], including 1894 patients, of whom 505 developed END. The NLR levels in patients with hemorrhagic stroke who developed END were similar to those without END (SMD = 0.84, CI 95% = −0.10-1.77, P value = 0.07).…”
Section: Resultsmentioning
confidence: 99%
“…After screening of the remaining 17 studies in full text, three studies without any data on NLR and END, two studies with missing SD data, one study including stroke patients suffering from cancer, one study without a control group, and one review article were excluded. Finally, nine articles were included in our study [15][16][17][18][19][20][21][22][23] (Figure 1).…”
Section: Eligible Studiesmentioning
confidence: 99%
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