Short-term outcome of patients with cardiac- and thrombo-embolic cerebral infarcts

Reuck, Jacques De; Vervaet, Veerle; Maele, Georges Van; Groote, Liesbeth De

doi:10.1016/j.clineuro.2008.02.015

Cited by 4 publications

(2 citation statements)

References 22 publications

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“…A number of mechanisms have been suggested to explain this increased mortality among stroke patients with atrial fibrillation, including a higher stroke severity,4,7,13–15 higher age,16 more comorbidity17,18 and poorer quality of care 6. However, the impact of these individual factors remains to be clarified.…”

Section: Introductionmentioning

confidence: 99%

Atrial fibrillation in patients with ischemic stroke: A population-based study

Thygesen¹,

Frost²,

Eagle³

2009

CLEP

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Background:Atrial fibrillation is a major risk factor for ischemic stroke. However, the prognostic impact of atrial fibrillation among patients with stroke is not fully clarified. We compared patient characteristics, including severity of stroke and comorbidity, quality of in-hospital care and outcomes in a cohort of first-time ischemic stroke patients with and without atrial fibrillation.Methods:Based on linkage of public medical databases, we did a population-based follow-up study among 3,849 stroke patients from the County of Aarhus, Denmark admitted in the period of 2003–2007 and prospectively registered in the Danish National Indicator Project.Results:Atrial fibrillation was associated with an adverse prognostic profile but not with an overall poorer quality of in-hospital care. Patients with atrial fibrillation had a longer total length of stay (median: 15 vs 9 days), and were at increased risk of in-hospital medical complications (adjusted relative risk = 1.48, 95% CI: 1.23–1.79) and recurrent stroke (adjusted hazard ratio = 1.30, 95% CI: 0.93–1.82) when compared with patients without atrial fibrillation. The adjusted hazard ratios for 30 days and one year mortality were 1.55 (95% CI: 1.20–2.01) and 1.55 (95% CI: 1.30–1.85), respectively. Patients not eligible to oral anticoagulant treatment had an increased risk of recurrent stroke (adjusted hazard ratio = 1.92, 95% CI: 1.19–3.11).Conclusion:Atrial fibrillation is associated with a poor outcome among patients with ischemic stroke particularly among patients, who are not eligible to oral anticoagulant treatment.

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Section: Introductionmentioning

confidence: 99%

Atrial fibrillation in patients with ischemic stroke: A population-based study

Thygesen¹,

Frost²,

Eagle³

2009

CLEP

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“…This may be explained by the fact that pretreated AH patients with an ischaemic stroke had more coronary artery disease and isolated atrial fibrillation [11]. …”

Section: Discussionmentioning

confidence: 99%

Stroke Characteristics in Patients with Pretreated Arterial Hypertension

Reuck

2010

Eur Neurol

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Background: Arterial hypertension (AH) is one of the most important vascular risk factors for stroke that can be treated. The present retrospective study analyses the influence of pretreated AH on the outcome of patients with ischaemic and haemorrhagic strokes, compared to those with normal blood pressure (BP). Patients and Methods: The demographic features, vascular risk factors, stroke type, stroke severity (according to the National Institutes of Health Stroke scale) and disability (according to the modified Rankin scale) were compared between 806 pretreated hypertensive patients and 320 ones with normal BP. Results: The incidence and the severity of the ischaemic strokes were similar but the outcome was worse in patients with pretreated AH compared to those with normal BP. In the former patients, coronary artery disease and isolated atrial fibrillation were found as confounders on multivariate analysis. The incidence, the severity and the outcome of patients with a haemorrhagic stroke were similar in both groups. Conclusions: The outcome in ischaemic stroke is worse in pretreated AH patients, compared to normotensive ones, probably due to the higher incidence of other associated vascular risk factors. Pretreated AH improves the outcome of patients with a haemorrhagic stroke.

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Burden of stroke in the Kingdom of Saudi Arabia: A soaring epidemic

Issrani

Gan

Prabhu

et al. 2021

Saudi Pharmaceutical Journal

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Stroke is a key cerebrovascular disease that is related to high morbidity and mortality in the globe. The Kingdom of Saudi Arabia (KSA) is not an exception where stroke is fast developing into a serious challenge due to the high mortality rate. Additionally, stroke presents a tremendous economic burden and has a devastating effect on the quality of lives of individuals. The number of stroke cases are increasing yearly, thus posing a major challenge to the health care system. Therefore, it is crucial to implement primary and secondary prevention strategies in the KSA. Nevertheless, as compared with developed countries, information on the prevalence, socio-demographic properties and prevention of stroke remains scarce that could be attributed to the shortage of research conducted in this specified region. The review is written to address the various aspects of stroke in the KSA, based on current literatures search using PubMed, Scopus, Web of Science and Google Scholar databases, to identify studies published since inception to Dec 2020.

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Short-term outcome of patients with cardiac- and thrombo-embolic cerebral infarcts

Cited by 4 publications

References 22 publications

Atrial fibrillation in patients with ischemic stroke: A population-based study

Atrial fibrillation in patients with ischemic stroke: A population-based study

Stroke Characteristics in Patients with Pretreated Arterial Hypertension

Burden of stroke in the Kingdom of Saudi Arabia: A soaring epidemic

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