Short-term precision assessment of trabecular bone score and bone mineral density using dual-energy X-ray absorptiometry with different scan modes: an in vivo study

Bandirali, Michele; Poloni, Alessandro; Sconfienza, Luca Maria; Messina, Carmelo; Papini, Giacomo Davide Edoardo; Petrini, Marcello; Ulivieri, Fabio Massimo; Leo, Giovanni Di; Sardanelli, Francesco

doi:10.1007/s00330-015-3606-6

Cited by 31 publications

(16 citation statements)

References 24 publications

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“…Secondly, DXA is able to measure BMD at those sites particularly relevant to osteoporotic fractures, such as lumbar spine and proximal femur, and measurements at these sites are optimal to predict fracture risk (17). The reproducibility of BMD measurements is very good, with a coefficient of variation (CoV) that ranges from 1% at lumbar spine to 2% at femoral neck (14,18,19). Lastly, DXA scans are widely available worldwide with very low scanning time (1-3 minutes).…”

Section: Dxamentioning

confidence: 99%

“…Trabecular bone score (TBS) is a recently implemented tool that provides a grayscale textural analysis of lumbar spine DXA images, showing the potential to be a BMDindependent fracture risk predictor (18,38,39). TBS is able to measures the variations in gray-level texture between adjacent pixels from DXA raw data; ex vivo studies confirmed that TBS was strongly correlate to micro-CT parameters, such as bone volume, tissue volume or trabecular number (40,41).…”

Section: Additional Tools Of Dxamentioning

confidence: 99%

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Diagnostic imaging of osteoporosis and sarcopenia: a narrative review

Messina

Maffi

Vitale

et al. 2018

Quant. Imaging Med. Surg.

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107

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Osteoporosis and sarcopenia represent two major health problems with an increasing prevalence in the elderly population. The correlation between these diseases has been widely reported, leading to the development of the term "osteosarcopenia" to diagnose those patients suffering from both diseases. Several imaging methods for the diagnosis and management of osteoporosis exist, with dual-energy X-ray absorptiometry (DXA) being the most commonly used for measuring bone mineral density (BMD). Imaging technique other than DXA is represented by conventional radiography, computed tomography (CT) and ultrasound (US). Similarly, the imaging technologies used to detect loss of skeletal muscle mass in sarcopenia include DXA, CT, US and magnetic resonance imaging (MRI). These methods differ in terms of reliability, radiation exposure and costs. CT and MRI represent the gold standard for evaluating body composition (BC), but are costly and time-consuming. DXA remains the most often used technology for studying BC, being quick, widely available and with low radiation exposure.

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Section: Dxamentioning

confidence: 99%

Section: Additional Tools Of Dxamentioning

confidence: 99%

Diagnostic imaging of osteoporosis and sarcopenia: a narrative review

Messina

Maffi

Vitale

et al. 2018

Quant. Imaging Med. Surg.

Self Cite

107

View full text Add to dashboard Cite

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“…24 On the other hand, TBS and BMD precision on iDXA instrument were found comparable, without significant differences between males and females (% coefficient of variation of L1-L4 BMD and TBS, 1.9% and 1.4%, respectively). 10 Accumulating evidence suggests that TBS used in addition to aBMD improves the prediction of osteoporotic fracture risk, 13,15,19,25,26 especially in patients with aBMD in the range of normality or osteopenia.…”

Section: Discussionmentioning

confidence: 88%

Trabecular bone score in healthy ageing

Bazzocchi¹,

Ponti²,

Diano³

et al. 2015

BJR

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“…13 This caution is derived from several limitations pertinent to TBS. These include the current lack of TBS cutoff values for fracture prediction, a reduced short-term intrascan precision of TBS in comparison with BMD, 14 and the presence of notable interscanner differences in TBS values. 15 Additional work on quality control (development of specific TBS phantoms, scanner cross-calibration) and further clinical studies are necessary to determine whether TBS will prove appropriate for routine clinical use.…”

Section: Techniques To Measure Bone Quality Trabecular Bone Scorementioning

confidence: 99%

Bone Quality—Beyond Bone Mineral Density

Link

Heilmeier

2016

Semin Musculoskelet Radiol

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Both bone mass and quality are responsible for bone strength. Whereas bone mass is measured with bone mineral density, quantification of bone quality is more complex and involves bone architecture, texture, and mechanical parameters. Over the last decade, significant progress has been made in developing technologies to measure bone quality. These include novel low-cost modalities such as trabecular bone score measured on dual-energy X-ray absorptiometry images and quantitative ultrasound as well as more advanced imaging modalities such as multidetector computed tomography, magnetic resonance imaging, and high-resolution peripheral quantitative computed tomography. We describe the reasons to measure bone quality and present the different modalities currently used to quantify it. This article also summarizes the strengths and weaknesses as well as the clinical feasibility of these technologies.

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Short-term precision assessment of trabecular bone score and bone mineral density using dual-energy X-ray absorptiometry with different scan modes: an in vivo study

Abstract: • TBS is an emerging tool for assessing BMD. • TBS reproducibility is lower than that of BMD. • Differences between imaging modes are not significant for either TBS or BMD.

Cited by 31 publications

References 24 publications

Diagnostic imaging of osteoporosis and sarcopenia: a narrative review

Diagnostic imaging of osteoporosis and sarcopenia: a narrative review

Trabecular bone score in healthy ageing

Bone Quality—Beyond Bone Mineral Density

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