Short-Term Results of Canaloplasty Surgery for Primary Open-Angle Glaucoma in Japanese Patients

Fujita, Katsuhide; Kitagawa, Kiyotaka; Ueta, Yoshiki; Nakamura, Tomoko; Miyakoshi, Akio; Hayashi, Atsushi

doi:10.1159/000324808

Cited by 21 publications

(7 citation statements)

References 4 publications

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“…In a small case series of Japanese patients receiving canaloplasty or phacocanaloplasty, performed by Fujita et al, 12 11 eyes of 9 Japanese patients with POAG underwent canaloplasty (3 eyes) or phacocanaloplasty (8 eyes). The mean preoperative IOP was 23.4±5.5 mmHg on 2.8±0.6 medications.…”

Section: Discussionmentioning

confidence: 99%

Combined phacocanaloplasty for open-angle glaucoma and cataract: 12 months results

Genaidy

Zein

Eid

2017

OPTH

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Purpose of the studyTo evaluate efficacy, safety, and success rates of canaloplasty combined with phacoemulsification and intraocular lens implantation in patients with open-angle glaucoma (OAG) and visually significant cataract.Patients and methodsA prospective interventional noncomparative case series carried out in Minia University Hospital from April 2015 to October 2016 on 20 eyes of 18 patients who had visually significant cataract and primary OAG. All the cases had combined phacocanaloplasty. Preoperative best-corrected visual acuity, intraocular pressure (IOP), and number of antiglaucoma medications were collected and compared to postoperative levels, and complications rates were recorded.Results20 eyes of 18 patients (5 males and 15 females), with a mean age 57.6 years (range 48–69 years), underwent phacocanaloplasty. Preoperative mean IOP was 25.20 ±1.009 mmHg. Postoperative IOP decreased to a mean of 14.20±0.9, 14.85±0.8, and 15.85±0.7 mmHG at 3, 6, and 12 months, respectively, with 37% reduction from preoperative IOP level at one year follow-up visit (P=0.0005). The number of antiglaucoma medications dropped from mean of 1.55 preoperatively to 0.35 postoperatively. LogMAR of best-corrected visual acuity improved from 0.6950±0.07 preoperatively to 0.3670±0.056, 0.3460±0.056, and 0.03370±0.052 at 3, 6, and 12 months postoperatively (P=0.0005). Complications were limited to mild hyphemia (one case), mild corneal edema (one case), and mild inflammatory membrane (one case) that resolved in the first week after surgery.ConclusionCanaloplasty combined with clear corneal phacoemulsification and intraocular lens implantation may be a safe and effective procedure to lower IOP in adult patients with OAG and visually significant cataract.

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Section: Discussionmentioning

confidence: 99%

Combined phacocanaloplasty for open-angle glaucoma and cataract: 12 months results

Genaidy

Zein

Eid

2017

OPTH

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“…The most frequent intraoperative complication was the creation of a false-passage creation (3.3%), and postoperative complication was mild hyphema (45.5%), respectively. 9 , 17 Some authors have suggested that average IOP following canaloplasty is not low enough. Therefore, canaloplasty should be considered for patients with mild-to-moderate glaucoma.…”

Section: Discussionmentioning

confidence: 99%

Ocular Decompression Retinopathy Following Canaloplasty for Primary Open Angle Glaucoma

Alantaree²,

Wang³

et al. 2016

Medicine

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Ocular decompression retinopathy (ODR), a rare postoperative complication following glaucoma surgery, is characterized by the transient appearance of scattered retinal hemorrhages.Here, we present a unique case of ODR in a patient with primary open angle glaucoma who underwent canaloplasty. A 31-year-old male patient presented with an intraocular pressure (IOP) of 60 mm Hg in the right eye. The IOP remained over 40 mm Hg, even when treated with maximum tolerated antiglaucoma medication. Canaloplasty drastically lowered IOP in the right eye from 40 to 7 mm Hg. However, fundus examination revealed ODR after surgery. The patient was treated with tobramycin and dexamethasone. Three months after canaloplasty, IOP remained in control at 16 mm Hg and all retinal hemorrhages had completely resolved.This case demonstrates that ODR can occur following canaloplasty and physicians should be aware of this potential complication in patients with severely elevated IOP. Sufficiently lowering IOP before surgery and gradually decreasing IOP during surgery may prevent ODR from occurring.

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“…Recent studies revealed a significant decrease in IOP by approximately 40% with a reduction of medications from 2.3 to 1.0 [ 4 , 27 – 29 ] and less surgical complications in canaloplasty than in trabeculectomy [ 30 – 34 ]. A number of retrospective and prospective studies found better results concerning IOP reduction in combined surgical (phacocanaloplasty) cases compared with canaloplasty [ 32 , 33 ].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Outflow StructuresIn Vivoafter the Phacocanaloplasty

Paulaviciute-Baikstiene

Vaičiulienė

Jašinskas

et al. 2016

Journal of Ophthalmology

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Purpose. To evaluate the in vivo changes in Schlemm's canal (SC) and the trabecular meshwork (TM) in patients with primary open-angle glaucoma (POAG) after phacocanaloplasty using anterior segment optical coherence tomography (AS-OCT). Methods. Ten eyes of nine patients with POAG (6 men and 3 women) who underwent phacocanaloplasty. Preoperative and postoperative visual acuity (VA), intraocular pressure (IOP), and use of glaucoma medications were evaluated. The main outcome measures were the area of SC and TM thickness assessed using AS-OCT before and 12 months after surgery. Results. We found statistically significant reduction in IOP (from 26.4 (8.6) mmHg to 12.9 (2.5) (p < 0.05) mmHg), increase in VA from 0.7 (0.4) to 0.9 (0.2), and decrease in glaucoma medication from 2.6 (1.2) to 1.1 (1.3) at 12 months postoperatively. There was a significant increase in the SC area (3081.7 (842.8) μm2 versus 5098.8 (1190.5) μm2, p < 0.001) and a decrease in mean TM thickness (91.2 (18.6) μm versus 81.3 (15.1) μm, p = 0.001) after surgery. We found negative correlations between SC area and IOP before surgery (r = −0.67, p = 0.03) and also between SC area before and IOP reduction 12 months after the phacocanaloplasty (r = −0.80, p = 0.005). Conclusions. Our results showed statistically significant dilation of SC area and reduction of TM thickness after phacocanaloplasty in POAG patients. The degree of SC expansion was related to the IOP decrease.

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Short-Term Results of Canaloplasty Surgery for Primary Open-Angle Glaucoma in Japanese Patients

Cited by 21 publications

References 4 publications

Combined phacocanaloplasty for open-angle glaucoma and cataract: 12 months results

Combined phacocanaloplasty for open-angle glaucoma and cataract: 12 months results

Ocular Decompression Retinopathy Following Canaloplasty for Primary Open Angle Glaucoma

Evaluation of Outflow StructuresIn Vivoafter the Phacocanaloplasty

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