Ortner's syndrome is an uncommon clinical condition characterized by hoarseness caused by recurrent laryngeal nerve (RLN) palsy in cardiovascular illness. A series of three cases of Ortner's syndrome involving the RLN was collected, and the cases were treated with injection laryngoplasty. We evaluated the cardiovascular abnormalities, status of vocal fold paralysis, and voice outcome after injection laryngoplasty. The causes in these three cases of Ortner's syndrome were a sac-like aneurysm of the aortic arch combined with an intramural thrombus, an intramural hematoma of the aortic arch, and a dissection-like giant aneurysm in the aortic arch directed inferiorly. All patients received an injection laryngoplasty using hyaluronic acid and their voice was improved after injection laryngoplasty. The possibility of cardiovocal syndrome should be kept in mind in cardiovascular disease patients with hoarseness. Injection laryngoplasty can be easily performed for achieving proper production of voice in a clinic setting.