Short‐term wound complications and predictive variables for complication after limb amputation in dogs and cats

Raske, Matthew; McClaran, Janet Kovak; Mariano, Andrea

doi:10.1111/jsap.12330

Cited by 25 publications

(24 citation statements)

References 27 publications

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“…24,25 SSI is diagnosed in up to 68% of cases after limb-sparing surgery, whereas SSI is diagnosed in up to 12.8% cases after amputation. 20,26 The effect of SSI on MST in the curativeintent treatment of OSA with amputation is unknown, justifying clinical investigation.…”

Section: Introductionmentioning

confidence: 99%

Effect of surgical site infection on survival after limb amputation in the curative‐intent treatment of canine appendicular osteosarcoma: a Veterinary Society of Surgical Oncology retrospective study

Hans¹,

Pinard

Nimwegen

et al. 2018

Veterinary Surgery

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Objective To determine the influence of surgical site infection (SSI) on the median disease‐free interval (DFI) and median survival time (MST) in dogs after amputation in the curative‐intent treatment of appendicular osteosarcoma (OSA). Study design Multi‐institutional retrospective cohort study. Animals Fifteen dogs with OSA and SSI, and 134 dogs with OSA and no SSI. Methods Medical records were reviewed, and dogs were included if the following criteria were met: histologic confirmation of OSA, no evidence of metastasis, ≥1 chemotherapy treatment, and available follow‐up data. We used the definition of SSI from the Centers for Disease Control and Prevention. Kaplan‐Meier estimates of median DFI and MST for the SSI and non‐SSI groups were compared by log‐rank test. Univariate and multivariate Cox proportional hazard regression analysis was evaluated for associations with DFI and survival. Results The median DFI and MST of all OSA dogs were 236 days (95% CI, 181‐283) and 283 days (95% CI 237‐355), respectively. The median DFI of dogs with SSI (292 days) did not differ from that of dogs without SSI (224 days, P = .156). The MST of dogs with SSI (292 days) did not differ from that of dogs without SSI (280 days, P = .417). Failure to complete chemotherapy was associated with decreased DFI and survival (P < .001). Adjustments for chemotherapy completion found no effect of SSI on survival. Conclusion SSI did not influence the survival of dogs with appendicular OSA treated with amputation and curative‐intent treatment. Clinical significance The extended survival associated with SSI after limb‐spare surgery for OSA does not appear to be present after amputation. Interactions between the canine immune system and OSA warrant additional study.

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Section: Introductionmentioning

confidence: 99%

Effect of surgical site infection on survival after limb amputation in the curative‐intent treatment of canine appendicular osteosarcoma: a Veterinary Society of Surgical Oncology retrospective study

Hans¹,

Pinard

Nimwegen

et al. 2018

Veterinary Surgery

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“…The complication rate with proximal (coxofemoral disarticulation or forequarter amputation) amputations is low. Major complications include wound dehiscence, pneumonia, contralateral limb arthrosis, haemorrhage, dehiscence, and surgical site infection which is reported in 12.8% of dogs (1,3). Poorly recognized complications include neuroma formation, cervical disc herniation and phantom pain (1).…”

Section: Introductionmentioning

confidence: 99%

Clinical outcome and complications of thoracic and pelvic limb stump and socket prostheses

Phillips

Kulendra²,

Bishop³

et al. 2017

Vet Comp Orthop Traumatol

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Stump socket prostheses are feasible and versatile in animals. In correctly selected cases, good to excellent outcomes are possible. However, complications are frequent but often manageable. Further investigations are required into the risk factors for poor outcomes and prospective studies are required to assess changes in biomechanics, function, and QOL before and after fitting of a stump socket prosthesis. Until further evidence is available, careful consideration should be given before fitting bilateral thoracic limb stump socket prostheses or thoracic limb stump socket prostheses to small breed dogs.

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“…After limb amputation, substantial dead space might exist, and therefore seroma formation is not uncommon, especially in large breed dogs (Raske et al, 2015). A seroma develops due to the accumulation of a serohemorrhagic fluid, produced due to postoperative inflammation with bleeding and leakage from capillaries (Amsellem, 2011;Kilpadi and Cunningham, 2011).…”

Section: Discussionmentioning

confidence: 99%

“…Besides seroma prevention, CIM with NPWT may also prevent surgical site infections (SSI) (Stannard et al, 2012;Horch, 2015;Suh et al, 2016). Factors that elicit SSI are surgical trauma to the soft tissues, excessive blood loss and substantial release of pain mediators, and/or long surgery time (Straw and Withrow, 1996;Kirby and Mazuski, 2009;Widgerow and Kalaria, 2012;Raske et al, 2015). Infections slow down the healing process, resulting in weak suture lines and an increased risk of wound dehiscence (Raske et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

“…Factors that elicit SSI are surgical trauma to the soft tissues, excessive blood loss and substantial release of pain mediators, and/or long surgery time (Straw and Withrow, 1996;Kirby and Mazuski, 2009;Widgerow and Kalaria, 2012;Raske et al, 2015). Infections slow down the healing process, resulting in weak suture lines and an increased risk of wound dehiscence (Raske et al, 2015). Closed incision NPWT may prevent SSI because tissue perfusion is enhanced, while environmental contamination of the wound is prohibited (Stannard et al, 2012;Horch, 2015;Suh et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

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Incisionele negatieve-druktherapie na voorpootamputatie bij een hond

Go¹,

Vallarino²,

Devriendt³

et al. 2018

Vlaams Diergeneeskundig Tijdschrift

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A four-year-old male castrated German shepherd dog was presented with severe left front leg lameness due to a fibrosarcoma lateral to the elbow. The ill-defined mass was not amendable to wide local excision and a curative-intent limb amputation was performed. Immediately postoperatively, closed incision management with negative pressure wound therapy (NPWT) was applied to minimize the risk of postoperative complications. The incision line was covered with a PrevenaTM dressing attached to a NPWT pump set at a continuous negative pressure of -125 mmHg. The dressing was removed 72 hours later. No wound complications were evident and further healing was unremarkable.

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Short‐term wound complications and predictive variables for complication after limb amputation in dogs and cats

Abstract: Short-term wound complications following pelvic or thoracic limb amputation in cats and dogs were typically minor and resolved after treatment.

Cited by 25 publications

References 27 publications

Effect of surgical site infection on survival after limb amputation in the curative‐intent treatment of canine appendicular osteosarcoma: a Veterinary Society of Surgical Oncology retrospective study

Effect of surgical site infection on survival after limb amputation in the curative‐intent treatment of canine appendicular osteosarcoma: a Veterinary Society of Surgical Oncology retrospective study

Clinical outcome and complications of thoracic and pelvic limb stump and socket prostheses

Incisionele negatieve-druktherapie na voorpootamputatie bij een hond

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