2021
DOI: 10.3389/fcvm.2021.691665
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Short-Time Changes in Coronary Artery Plaques Assessed by Follow-Up Coronary CT Angiography—Characteristics and Impact on Patient Management

Abstract: Background: Coronary artery disease (CAD) shows a chronic but heterogeneous clinical course. Coronary CT angiography (CTA) allows for the visualization of the entire coronary tree and the detection of early stages of CAD. The aim of this study was to assess short-time changes in non-calcified and mixed plaques and their clinical impact using coronary CTA in a real-world setting.Methods: Between 11/2014 and 07/2019, 6,701 patients had a coronary CTA with a third-generation dual-source CT, of whom 77 patients (5… Show more

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“…With excellent sensitivity and negative predictive value, coronary CT angiography (CCTA) has developed into one of the first choices of non-invasive diagnostic strategies for the evaluation of coronary artery disease (CAD) during clinical practice (1)(2)(3)(4). However, on account of the blooming and beam hardening artifacts, the accuracy of stenosis evaluation related to calcified plaques was still unsatisfactory, since the calcification might lead to overestimation of the stenosis and excessive downstream testing (5)(6)(7).…”
Section: Introductionmentioning
confidence: 99%
“…With excellent sensitivity and negative predictive value, coronary CT angiography (CCTA) has developed into one of the first choices of non-invasive diagnostic strategies for the evaluation of coronary artery disease (CAD) during clinical practice (1)(2)(3)(4). However, on account of the blooming and beam hardening artifacts, the accuracy of stenosis evaluation related to calcified plaques was still unsatisfactory, since the calcification might lead to overestimation of the stenosis and excessive downstream testing (5)(6)(7).…”
Section: Introductionmentioning
confidence: 99%