Shotgun metagenomic analysis of bacterial symbionts associated with “Chromodoris quadricolor” mantle

Mahmoud, Engy; Hanora, Amro; Abdalla, Salah; Ahmed, Ali A Abdelrahman; Zakeer, Samira

doi:10.1016/j.margen.2023.101030

Cited by 1 publication

(1 citation statement)

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“…These bacterial symbionts provide the nudibranch with essential nutrients and chemical defense against predators. Bacterial communities of Chromodoris quadricolor mantle, a Red Sea nudibranch, were detected to encode many potential BGCs that would help produce different natural products (Mahmoud et al, 2023). The presence of several pathways related to antimicrobial and secondary metabolites biosynthesis suggested that the nudibranch host has these bacterial symbionts as protecting members.…”

Section: Natural Products Of Mollusks' Bacterial Symbiontsmentioning

confidence: 99%

Marine mollusks are a good source of natural products

Mahmoud,

Abdelrahman,

Hanora

et al. 2023

Records of Pharmaceutical and Biomedical Sciences

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Almost all marine ecosystems have Mollusca members for their balanced continued functioning. While some may seem harmless or even gentle, others are equipped with powerful weapons like venomous tentacles to fend off predators. Mollusks are considered an important subject of research in various fields due to their unique biology and ecological significance. Their research has many implications in areas such as medicine and biotechnology. Numerous species have recently been the subject of research, with numerous secondary metabolites being isolated and their chemical structures being clarified. Natural substances that were poisonous to tumor cells, harmful bacteria, viruses, and others have been discovered. Some isolated compounds constituted the active ingredients in medicinal preparations used in clinical practice, while others are still in various stages of preclinical research. These substances often lacked equivalents in other naturally occurring substances with terrestrial origin. Metagenomics tools has simplified the discoveries in this field and with the help of metagenomics, we could identify new genes and proteins to be used in biotechnology applications, such as the development of new drugs.

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Section: Natural Products Of Mollusks' Bacterial Symbiontsmentioning

confidence: 99%