2019
DOI: 10.1101/679985
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Shotgun Metagenomics of 361 elderly women reveals gut microbiome change in bone mass loss

Abstract: Bone mass loss contributes to the risk of bone fracture in elderly. Many factors including age, obesity, estrogen and diet, are associated with bone mass loss. Some mice transplantation experiments suggest that the intestinal microbiome might influence the bone mass by regulating the immune system. However, there has been little evidence from human studies, not to mention the metagenome-wide association studies (MWAS).We have recruited 361 Chinese elderly women to explore the influence of gut microbiome on bon… Show more

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