Should donor body mass index influence kidney utilization by transplant centers?

Sharif, Adnan

doi:10.1111/tri.13529

Cited by 1 publication

(1 citation statement)

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“…38 Further investigation on the potential protective effect of increased kidney donor BMI on BKV infection is warranted and highlights the need for ongoing investigation in the use of allografts from obese donors, as negative outcomes related to recipient obesity may be inappropriately creating selection bias. 39 Our study has the expected limitations of being a single-center study, with results reflective of our specific clinical protocols and patient population. Our approach of adjusting immunosuppression only for BK PCR >1000 copies/ml may not be common practice in other centers.…”

Section: Discussionmentioning

confidence: 96%

Risk factors and outcomes of BK viremia among deceased donor kidney transplant recipients based on donor characteristics

Breyer

Dodin

Djamali

et al. 2021

Transplant Infectious Dis

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Introduction: BK polyomavirus (BKV) is a common infection among kidney transplant recipients (KTR). Risk factors and outcomes based on donor characteristics remain largely unknown. Methods:In this study, we aimed to analyze the impact of donor factors through a paired kidney analysis. We included 289 pairs of adult deceased donor transplants (578 KTRs total); each pair had received kidneys from the same donor. Recipient pairs were divided into three groups: "no BK group" if neither KTR developed BK viremia (n = 336), "discordant" if the only one did (n = 176), and "concordant" if both did (n = 66).Acute rejection (AR), graft failure, and BK nephropathy (BKN) were outcomes of interest.Results: Donors in the concordant group were younger, had lower kidney donor profile index (KDPI), and were less likely to be donor after circulatory death (DCD). In multivariate analyses, KTRs who had a donor with a higher body mass index (BMI)

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Section: Discussionmentioning

confidence: 96%