Should every unclear neuromuscular symptom be termed ?paraneoplastic??

Carter, Gregory T.; Fritz, Russell C.

doi:10.1002/(sici)1097-4598(199709)20:9<1205::aid-mus23>3.0.co;2-q

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2016

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“…Recurrent cases are rare (6,40-50). Furthermore, the response to NSAIDs is often good even in cases of repeated relapse (41-43), and some cases of spontaneous remission have occurred (8,49). Steroid-resistant cases are also rare (47,51).…”

Section: Discussionmentioning

confidence: 99%

Recurrent Bilateral Focal Myositis

et al. 2016

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This report describes a rare case of recurrent bilateral focal myositis and its successful treatment via methotrexate. A 38-year-old man presented myalgia of the right gastrocnemius in May 2005. Magnetic resonance imaging showed very high signal intensity in the right gastrocnemius on short-tau inversion recovery images. A muscle biopsy revealed inflammatory CD4+ cell-dominant myogenic change. Focal myositis was diagnosed. The first steroid treatment was effective. Tapering of prednisolone, however, repeatedly induced myositis relapse, which progressed to multiple muscle lesions of both lower limbs. Initiation of methotrexate finally allowed successful tapering of prednisolone, with no relapse in the past 4 years.

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