Should naevus sebaceus be excised prophylactically? A clinical audit

Barkham, Melissa C.; White, Nicholas J.; Bründler, M. A.; Richard, Bruce; Moss, Celia

doi:10.1016/j.bjps.2007.03.038

Cited by 32 publications

(26 citation statements)

References 4 publications

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“…In the past, the malignant potential of sebaceous nevi has been overestimated. 96,97 Their surgical removal may be considered for cosmetic and psychosocial reasons but, according to present knowledge, cancer prophylaxis cannot be taken as a rationale to remove such nevi. Numerous earlier reported ''basal cell carcinomas'' may in fact have been trichoblastomas.…”

Section: Schimmelpenning Syndromementioning

confidence: 98%

The group of epidermal nevus syndromes

Happle

2010

Journal of the American Academy of Dermatology

212

171

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Section: Schimmelpenning Syndromementioning

confidence: 98%

The group of epidermal nevus syndromes

Happle

2010

Journal of the American Academy of Dermatology

212

171

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“…For this reason, NSJ should be managed with surgery before the period of puberty, as was proposed in many reports [48,49]. CO 2 lasers [50] enhance cosmesis, but can only reach the papillary dermis, therefore they are not recommended because of the possibility of malignant degeneration of the remaining cells in the lower dermis [51].…”

Section: Discussionmentioning

confidence: 99%

Dermoscopic Analysis of Nevus Sebaceus of Jadassohn: A Study of 13 Cases

Kelati

Baybay

Gallouj

et al. 2017

Skin Appendage Disord

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Background: Nevus sebaceus of Jadassohn (NSJ) is a complex cutaneous hamartoma with various clinical appearances. Aim: To describe different dermoscopic patterns of this nevus according to its evolutionary stages. Methods: This was an analytical study of NSJ carried out in the Department of Dermatology at the University Hospital Hassan II, Fez, Morocco. Results: Thirteen patients with a NSJ were enrolled in the study. Elevated verrucous plaques were noticed in 9 patients, homogeneous tumors were described in 2 NSJ, an alopecic patch was found in 1 case, and we had 1 case of malignant transformation into basal cell carcinoma. The dermoscopic aspects of NSJ described in our study were yellowish or brown globules aggregated in clusters on a yellow background. This pattern was significantly related to the first stage of an alopecic patch (p = 0.001). Whitish-yellow lobular aspect and grayish papillary appearance were significantly related to verrucous plaques (p = 0.003). Homogeneous yellow-whitish pattern was related to nodules (p = 0.005). Conclusion: The establishment of specific dermoscopic features of NSJ according to its evolutionary stages is important for its diagnosis and especially its monitoring in order to detect malignant transformation.

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“…Most are present at birth, although some emerge in early childhood. It is an uncommon birthmark, occurring in 0.3% of all neonates, and is more common in females [3]. The natural history of the lesion demonstrates evolution, following the typical differentiation of normal sebaceous glands.…”

Section: Discussionmentioning

confidence: 95%