Should prospective renal transplant recipients be screened for <i>Strongyloides stercoralis</i>?

Arkell, Paul; Pan, Daniel; Riley, Peter; Cooper, Philip J.; MacPhee, Ian W.; Cosgrove, Catherine; Brincat, Stephan

doi:10.1093/ckj/sfaa047

Cited by 4 publications

(2 citation statements)

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“…Strongyloidiasis is caused by infection with Strongyloides stercoralis which is an intestinal nematode and is widely found in tropical and subtropical countries (2,3). Humans are the final hosts in the parasite cycle which has autoinfection which is rare and charecterstic feature in its life cycle (2,4).…”

Section: Introductionmentioning

confidence: 99%

“…Immunosuppressed patients (e.g. taking exogenous corticosteroids or immunsuppressive drugs, solid organ tansplantation) are at risk for life-threating complication like hyperinfection syndrome and disseminated tissue infestation (2,4). Mortality rate can be approaches upto 50% in hyperinfection syndrome and upto 70% in disseminated disease (6,7).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Multiorgan failure due to strongyloides infection in liver transplant recipient: A case report and literature review

EKMEN¹,

BİLGER²,

KİRMAN³

et al. 2022

JECM

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Strongyloidasis is caused by an intestinal nematode Strongyloides stercoralis which is widely distributed in tropical and subtropical countries. In immunocompetent individuals, Strongloides stercoralis infection usually does not produce any symptoms or causes gastrointestinal, cardiopulmonary, or skin symptoms. However, in some patients especially immunsupressive (e.g post-transplant, taking exogenous corticosteroids), its infection associated with severe and life-threatening disease like hyperinfection syndrome and disseminated tissue infestation. The limitation of diagnostic test make it challenging to diagnose strongyloidasis. Therefore, it is important to suspect infection of Strongyloides stercoralis. We describe a case of Strongiloides infection with a fatal outcome in liver transplant recipient.

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