Should “Retro-ocular Pain, Photophobia and Visual Acuity Loss” Be Recognised as a Distinct Entity? The ROPPVAL Syndrome

Pellegrini, F.; Mandarà, Erika; Brocca, Daniele

doi:10.1080/01658107.2021.1887289

Cited by 1 publication

(1 citation statement)

References 21 publications

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“…The site of optic nerve injury is generally within the anterior part of the optic nerve. In these instances, the visual acuity of the unilateral eye typically decreases significantly without pain [ 57 ]. There are some cases of bilateral acute optic nerve anterior injury in clinical practice.…”

Section: Introduction Of Optic Nerve Injury Ophthalmopathy and Animal...mentioning

confidence: 99%

Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

et al. 2023

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Optic nerve damage is a common cause of blindness. Optic nerve injury is often accompanied by fundus vascular disease, retinal ganglion cell apoptosis, and changes in retinal thickness. These changes can cause alterations in protein expression within neurons in the retina. Proteomics analysis offers conclusive evidence to decode a biological system. Furthermore, animal models of optic nerve injury made it possible to gain insight into pathological mechanisms, therapeutic targets, and effective treatment of such injuries. Proteomics takes the proteome as the research object and studies protein changes in cells and tissues. At present, a variety of proteomic analysis methods have been widely used in the research of optic nerve injury diseases. This review summarizes the application of proteomic research in optic nerve injury diseases and animal models of optic nerve injury. Additionally, differentially expressed proteins are summarized and analyzed. Various optic nerve injuries, including those associated with different etiologies, are discussed along with their potential therapeutic targets and future directions.

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Section: Introduction Of Optic Nerve Injury Ophthalmopathy and Animal...mentioning

confidence: 99%

Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

et al. 2023

View full text Add to dashboard Cite

show abstract

Should “Retro-ocular Pain, Photophobia and Visual Acuity Loss” Be Recognised as a Distinct Entity? The ROPPVAL Syndrome

Cited by 1 publication

References 21 publications

Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

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