Should the methicillin-resistant Staphylococcus aureus carriage status be used as a guide to treatment for skin and soft tissue infections?

Plastic and Reconstructive Surgery

Erba

et al. 2015

Self Cite

Treatment of septic hand tenosynovitis is complex, and often requires multiple débridements and prolonged antibiotic therapy. The authors undertook this study to identify factors that might be associated with the need for subsequent débridement (after the initial one) because of persistence or secondary worsening of infection. METHODS: In this retrospective single-center study, the authors included all adult patients who presented to their emergency department from 2007 to 2010 with septic tenosynovitis of the hand

Section: Discussionmentioning

confidence: 99%

Septic Tenosynovitis of the Hand

Müller

Plastic and Reconstructive Surgery

Erba

et al. 2015

Self Cite

“…Skin commensals such as coagulase-negative staphylococci, corynebacteria, or Bacillus spp, and low-virulence organisms such as enterococci, can usually be ignored unless cultured from deep, aseptically collected tissue or infections involving osteosynthetic material or hardware. Likewise, the mere presence of skin or mucosal colonization with healthcare-associated MRSA does not oblige the clinician to empirically cover this organism, 40,41 even in the presence of underlying osteosynthetic material. 42 Quantitative cultures, which were in vogue in the past, are now rarely done as they are difficult to perform, expensive, and do not add much to deciding which wounds are infected or what organisms to treat.…”

Section: Systemic Antimicrobial Therapymentioning

confidence: 99%

Diabetic foot infections: what have we learned in the last 30 years?

International Journal of Infectious Diseases

Aragón‐Sánchez

Lew

et al. 2015

Self Cite

138

141

“…Skin colonization due to healthcare‐associated methicillin‐resistant S. aureus (MRSA) does not always require anti‐MRSA coverage .…”

Section: Treatmentmentioning

confidence: 99%

Diabetic foot infections: state‐of‐the‐art

Diabetes Obesity Metabolism

Gariani

Pataky³

et al. 2013

138

153

Foot infections are frequent and potentially devastating complications of diabetes. Unchecked, infection can progress contiguously to involve the deeper soft tissues and ultimately the bone. Foot ulcers in people with diabetes are most often the consequence of one or more of the following: peripheral sensory neuropathy, motor neuropathy and gait disorders, peripheral arterial insufficiency or immunological impairments. Infection develops in over half of foot ulcers and is the factor that most often leads to lower extremity amputation. These amputations are associated with substantial morbidity, reduced quality of life and major financial costs. Most infections can be successfully treated with optimal wound care, antibiotic therapy and surgical procedures. Employing evidence-based guidelines, multidisciplinary teams and institution-specific clinical pathways provides the best approach to guide clinicians through this multifaceted problem. All clinicians regularly seeing people with diabetes should have an understanding of how to prevent, diagnose and treat foot infections, which requires familiarity with the pathophysiology of the problem and the literature supporting currently recommended care.