Should urine antigen testing for<i>Legionella pneumophila</i>be ordered for all hospitalized patients with community-acquired pneumonia?

Cheek, A.; Jackson, Ian; Velagapudi, Manasa; Narechania, Shraddha

doi:10.3949/ccjm.90a.22039

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Is Legionella Urinary Antigen Test Enough?1

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2024

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“…9 The sensitivity of the UAT varies depending on the serogroup of Legionella, the severity of the disease, and the time since the onset of symptoms. 10 For example, the sensitivity of the UAT for L. pneumophila serogroup 1, the most common serogroup that causes Legionnaires' disease, is about 70% in patients with severe pneumonia, but only about 40% in patients with mild pneumonia. 11 The UAT also has some disadvantages, such as the inability to detect Legionella species other than L. pneumophila serogroup 1 and the inability to diagnose relapse or reinfection due to the persistence of antigen excretion.…”

Section: Is Legionella Urinary Antigen Test Enough?mentioning

confidence: 99%

Practicing Medicine Wisely: Routine Use of Urine Legionella in Suspicious Pneumonia – Are we Overdoing?

Gautam,

Neupane,

Mercado

et al. 2024

J Nepal Med Assoc

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Legionella spp. is an underreported cause of Community Acquired pneumonia that affects significant population specially in urban areas and its prevalence is on an increasing trend. The routine practice of testing for urinary antigen of Legionella in all suspected cases of pneumonia is prevalent is resource rich western countries. Although several studies have shown no distinct advantage of performing routine urinary antigen testing, this practice continues to be preferred by clinicians. In this viewpoint, we have discussed the advantages and disadvantages of urinary antigen testing, its relevance in current practice and its impact on clinical outcomes.

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Section: Is Legionella Urinary Antigen Test Enough?mentioning

confidence: 99%