Sialoblastoma: A literature review from 1966-2011

Abstract

Sialoblastoma is a rare congenital tumour of the salivary glands arising mainly from the parotid gland. It is usually diagnosed at birth or shortly thereafter with a significant variability in histological appearance and clinical course. In extensive search of PubMed indexed journals, we got 46 cases of “sialobalstoma/embryoma/congenital basal adenoma”, with one case was of German literature and three additional cases of adult sialobalstoma. This article has extensively reviewed the clinical, histopathological and immunohistochemical features, Magnetic resonance imaging (MRI) and Computerized Tomography (CT) findings, treatment and prognosis.

Two Synchronous Neonatal Tumors: An Extremely Rare Case

“…Treatment of sialoblastoma involves complete surgical excision with tumor-free margins and chemotherapy previous to surgery to reduce the tumor or when local recurrence (22%) or lung metastasis occurs [ 3 , 5 , 13 ].…”

“…Hepatoblastoma is the most common malignant tumor of the liver in childhood; however, incidence is less than 10% in neonates. In our case, the histologic type was epithelial of the mixed embryonal/fetal subtype according to the liver tumor consensus classification [ 5 ].…”

Sialoblastoma of the parotid gland in a 13‐year‐old girl with multiple recurrences and long‐term follow‐up

“…It seems that boys are more frequently affected. The tumor seems to have a predilection for the parotid gland, whereas the submandibular gland or the minor salivary glands are rarely involved …”

Progressive Metastatic Sialoblastoma in a Young Child: Challenges in Treatment

“…Age of presentation is reported from the prenatal period to 4 years. [1] Sitthichaiyakul et al observed that the median age of diagnosis was 9.8 years. [2] There have also been isolated case reports of sialoblastoma in adults.…”