Sialolipoma of the parotid gland

Michaelidis, Ioannis George-Akrivos; Stefanopoulos, Panagiotis K.; Sambaziotis, Demetrios; Zahos, Marios Alexandros; Papadimitriou, George Alexandros

doi:10.1016/j.jcms.2005.08.008

Cited by 27 publications

(27 citation statements)

References 7 publications

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“…Its morphology strictly recapitulates that of sialolipoma, [9][10][11] being composed of normal looking acinar and ductal structures with interposed mature adipocytes. At variance with sialolipoma, the current lesion also included a prominent vascular component, consisting in capillaries, venules, small arteries and cavernous vessels irregularly distributed throughout the mass.…”

Section: Discussionmentioning

confidence: 67%

“…The former [9][10][11] is a well-demarcated neoplasm that histologically shows mature adipocytes and glandular structures with distinct ductal, acinar, basal and myoepithelial cells, closely resembling the cellular composition of normal salivary glands. Lipoadenoma and its oncocytic variant [12][13][14][15] are well-circumscribed and encapsulated neoplasms comprising mature adipocytes and branching narrow tubules, sometimes without evident lumina formation, lined by columnar cells with interposed scattered basal cells.…”

Section: Introductionmentioning

confidence: 99%

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Hamartomatous Angiolipoma of the Parotid Gland (Sialoangiolipoma)

Maiorano

Capodiferro

Fanelli

et al. 2008

Head and Neck Pathol

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Mesenchymal tumors of the salivary glands are rare and mostly localized to the parotid gland. We report on the clinico-pathological features of a distinct parotid tumor occurred in a newborn, showing glandular structures admixed with mature lipocytes and blood vessels in variable proportions. This was a well-circumscribed and slowly growing nodule of the superficial parotid lobe, mostly reddish in color with white-yellowish striations. Microscopically, a distinct lobular architecture was evident, along with normal-appearing acinar and ductal structures with interposed loose fibrous stroma. The latter contained aggregates of mature lipocytes and variably sized blood vessels. The morphological features of the lesion reported herein recapitulate those of sialolipoma but also include the presence of a prominent vascular component intimately admixed with both the glandular and the adipose tissues. At variance with salivary lipoadenoma, the glandular component in the current case distinctly showed all the cellular components of normal salivary (serous) glands. In consideration of the young age of the patient, the minimal growth rate and the histological features of the lesion, we hypothesize a hamartomatous origin for this lesion and propose the designation of sialoangiolipoma.

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Section: Discussionmentioning

confidence: 67%

Section: Introductionmentioning

confidence: 99%

Hamartomatous Angiolipoma of the Parotid Gland (Sialoangiolipoma)

Maiorano

Capodiferro

Fanelli

et al. 2008

Head and Neck Pathol

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“…These tumors have been identiWed in both major salivary glands, particularly the parotid gland [8,34,35], and minor salivary glands [6,33,36,37]. In the latter, no preference for an anatomical site has been described, with reports of cases involving the hard palate [8,36], soft palate [8,33], Xoor of the mouth [11], buccal mucosa [33], tongue [6], and buccal sulcus [6].…”

Section: Discussionmentioning

confidence: 99%

Lipomas of the oral cavity: clinical and histopathologic study of 41 cases in a Brazilian population

Juliasse

Nonaka

Pinto

et al. 2009

Eur Arch Otorhinolaryngol

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This study evaluated the clinical and histopathologic aspects of 41 cases of oral lipomas diagnosed in a Brazilian population. All records from patients diagnosed with oral lipoma between 1970 and 2008 were reviewed. Histological sections were evaluated by light microscopy. There was a predominance of females (2.4:1), with a peak incidence between the sixth and seventh decade. The buccal mucosa was the most aVected site (53.7%), followed by the buccal sulcus (14.6%) and tongue (9.8%). Tumor size ranged from 0.5 to 10 cm and the mean reported duration was 48 months. Histologically, the following variants were identiWed: lipoma (41.5%), Wbrolipoma (34.1%), spindle cell lipoma (9.8%), sialolipoma (9.8%), osteolipoma (2.4%), and chondrolipoma (2.4%). Most tumors were well delimited, irrespective of the variant. Lipomas are rare tumors of the oral cavity. The characterization of new variants, such as sialolipomas, and the identiWcation of histological subtypes in already known variants, such as low-fat and fat-free spindle cell lipomas, highlight the importance for careful microscopic evaluation of these tumors, which might be combined with immunohistochemistry in some cases.

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“…In one reported case, total parotidectomy was required where the deep lobe of the parotid was involved 8. To date, there has only ever been one reported case of recurrence despite surgical excision, which has obvious implications for follow-up 9…”

Section: Discussionmentioning

confidence: 99%