Sichtbares Licht ermöglicht Ruthenium‐katalysierte meta‐C‐H‐Alkylierung bei Raumtemperatur

Abstract

Die durchs ichtbares Licht induzierte Rutheniumkatalyse ermçglicht meta-selektive C-H-Alkylierungen mit hoher Regioselektivitätu nter milden Bedingungen bei Raumtemperatur.D ie Metallaphotokatalyse erfolgt ohne zusätzlichen Photokatalysator und verfügt über eine große Anwendungsbreite.D ie Robustheit der photoinduzierten meta-C-H-Funktionalisierung spiegelt sich in einer hohen Toleranz für funktionelle Gruppen wider und legt die Grundlage füra nspruchsvolle,sekundäre und tertiäre meta-C-H-Alkylierungen mittels Rutheniumphotoredox-Katalyse.

Explorative Sonophotocatalytic Study of C-H Arylation Reaction of Pyrazoles Utilizing a Novel Sonophotoreactor for Green and Sustainable Organic Synthesis

“…In this case, an alkali metal base deprotonated a relatively acidic sp 2 C-H bond before transmetalation and coupling with an aryl halide were performed on it [55,56]. The known mechanism for the effect of visible light on catalytic reactions involving complexes (photocatalytic reactions) [57] was also taken into consideration, which involved single electron transfer (SET). Herein, the reaction proceeded by initial deprotonation of a relatively acidic sp 2 C-H bond by an alkali metal base (K 2 CO 3 ) forming an intermediate A, which was further enhanced by ultrasonic irradiation (step I, Scheme 3).…”

Advances of N-Hydroxyphthalimide Esters in Photocatalytic Alkylation Reactions

“…[1][2][3][4][5] Since the pioneering works independently were reported by Macmillan, [6] Yoon, [7] and Stephenson, [8] photocatalytic chemistry has ushered in a great renaissance in the past decade. [9][10][11][12][13][14][15][16][17][18][19][20] Accordingly, numerous compounds with photoredox activities, such as organic halides, [21][22][23][24][25] carboxylic acids, [26][27][28][29][30][31] and other heteroatoms (such as B, N, O, S, Se, P, or Si, etc. )-containing compounds, have been excavated as radical precursors for diverse organic transformations.…”