Sickle cell disease and COVID‐19: Atypical presentations and favorable outcomes

Clinical presentations and outcomes of COVID‐19 infection in sickle cell disease patients: Case series from Komfo Anokye teaching hospital, Ghana

“…Studies by Hussain et al and others mostly from outside Africa have shown good outcomes in SCD patients with COVID‐19 17,18,23 . Similarly, none of our patients had an adverse disease outcome.…”

“…In the absence of an effective, approved, drug therapy and vaccine against the virus, there is concern about the potential negative impact of the pandemic in SCD patients. Literature from France, the United Kingdom and America, 15‐19 have described the presentation and outcomes of COVID‐19 in SCD patients. There is, however, a scarcity of data on the impact of COVID‐19 on patients in Africa where an estimated 75% of people affected by SCD reside 7 .…”

Clinical outcomes of COVID-19 in patients with sickle cell disease and sickle cell trait: A critical appraisal of the literature

“…Overall, patients had short lengths of stay and no deaths. 5 (71) 0 (0) Azerad et al [ 109 ] Belgium 3 (1/2) 30 HbSS (3) HU (3) BT (3) SCD pts. showed mild clinical presentation of COVID-19, which can be misleading; If BT is performed, always consider risk of DHTR.…”

Sickle cell disease and COVID‐19: Susceptibility and severity

“…All patients received HU therapy. 28 Moreover, in a Senegalese SCD woman positive for COVID-19, the disease's clinical course was mild. 29 There are five studies from Middle East, including a Saudi Arabian family with COVID-19, mother was sickle cell trait without significant symptoms of COVID-19, and two of her HbSS children, recovered from COVID-19 with good outcome.…”