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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.Anti-Sd a is of no clinical significance, because it rarely causes hemolytic transfusion reactions. Even when its presence is suspected during antibody screening test, further identification of the antibody is usually not performed. We experienced a case of anti-Sd a in 73 yr-old male patient showing mixed field agglutination by microcolumn agglutination. Antibody specificity could not be identified by conventional antibody identification test, and it was proven to be anti-Sd a by urine neutralization test. In spite of its little clinical significance, it may give incompatible crossmatching results reacting with Sd a antigen, which occurs at a high frequency in general population. When incompatible crossmatch results arising from anti-Sd a are suspected, the problem may be solved by using the urine-neutralized serum of in crossmatching test.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.Anti-Sd a is of no clinical significance, because it rarely causes hemolytic transfusion reactions. Even when its presence is suspected during antibody screening test, further identification of the antibody is usually not performed. We experienced a case of anti-Sd a in 73 yr-old male patient showing mixed field agglutination by microcolumn agglutination. Antibody specificity could not be identified by conventional antibody identification test, and it was proven to be anti-Sd a by urine neutralization test. In spite of its little clinical significance, it may give incompatible crossmatching results reacting with Sd a antigen, which occurs at a high frequency in general population. When incompatible crossmatch results arising from anti-Sd a are suspected, the problem may be solved by using the urine-neutralized serum of in crossmatching test.
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