Siddha herbo-mineral drug Kandhaga Rasayanam in the treatment of Dermatophytoses (Padarthamarai)

Abstract

The symptoms of dermatophytosis goes congruent with the disease entity Padarthamarai in Siddha medicine. Kandhaga Rasayanam (KR) is a Siddha herbo-mineral formulation indicated for padarthamarai. In recent times, treatment of dermatophytosis challenge to dermatologists. The present study was carried out to clinically evaluate the efficacy of KR as a trial drug for Dermatophytosis. The objective of the present study was to study the efficacy of the drug KR in giving mycological and clinical cure. This was an open-label, non-randomized, single -arm clinical study in which 51 patients of either gender diagnosed with padarthamarai were included. The trial was registered in Clinical trials registry India with CTRI number CTRI/2012/01/002362. The treatment period was 45 days. Out of the 51 participants enrolled in this study, 45 participants were included in the final analysis based on their adherence to the conditions. 66.67% showed skin scraping negative for dermatophytes. There was a significant reduction in the clinical signs after the treatment without any adverse reactions. This trial has brought to limelight the efficacy of the Siddha drug Kandhaga Rasayanam in treating padarthamarai . Further, randomized controlled clinical trials are necessary to substantiate the traditional claim and make KR a plausible treatment option for Dermatophytosis.