Side effects from intense pulsed light: Importance of skin pigmentation, fluence level and ultraviolet radiation—A randomized controlled trial

Grunewald

2018

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Summary Technical advances in recent years have led to new dermatologic laser systems, light sources, and treatment concepts. Commonly used wavelengths – generated today with LED‐based devices – allow for the combination of various tissue effects and are associated with improved outcomes. Laser hair removal has become more efficient with the use of diode lasers that emit multiple wavelengths simultaneously. In the near future, novel LED‐based lasers will also be introduced for the treatment of vascular lesions. Here, too, the combination of different wavelengths promises to be beneficial. Picosecond lasers have led to advances in the field of pigment removal (tattoos).

Section: Uwe Paasch Sonja Grunewaldunclassified

2018 update on dermatologic laser therapy: Part 1 – epilation, vascular lesions and pigments

Grunewald

2018

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“…Avoiding UV exposure prior to and at least 24 hours after IPL treatment is of particular importance. Even the single application of > 3 SEDs (standard erythema dose) has been shown to cause numerous adverse effects such as erythema (87 %), purpura (27 %), blisters (20 %), edema (13 %), crusting (13 %), hyperpigmentation (60 %), and hypopigmentation (20 %) . Due to phototoxic reactions and bulk heating, tattoos in the epilation area are a recurrent source of adverse events.…”

Section: Epilationmentioning

confidence: 99%

“…Here, too, special care must be taken when treating tanned individuals. Following treatment, UV exposure should be avoided for at least 24 hours .…”

Section: Vesselsmentioning

confidence: 99%

“…In accordance with the concept of selective photothermolysis, only systems with very short pulse durations may be used for tattoo removal in order to minimize any collateral damage. A common problem is the competing target chromophore melanin , which renders the procedure exceedingly prone to complications. In addition, the removal of dyes from the human skin is associated with risks such as allergic reactions (especially for red dyes), color changes, formation of toxic degradation products, scarring, and incomplete removal even after many sessions .…”

Section: Pigment Removalmentioning

confidence: 99%

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New lasers and light sources – old and new risks?

Schwandt²,

Seeber

et al. 2017

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Recent developments (new wavelengths, treatment concepts, and combinations) in the field of lasers, intense pulsed light (IPL), LED, as well as new energy and light sources have opened up new therapeutic options that extend beyond mere aesthetic indications. Thus, while fractional lasers used to be employed to merely treat wrinkles, the same devices - in the context of laser-assisted drug delivery - have now become important tools in the treatment of scars, field cancerization, and epithelial tumors. The requirements posed to physicians, both with respect to establishing the indication and conducting treatment, have been growing along with the increase in technological complexity as well as the rising number of comorbidities and comedications in a patient population that continues to age. At the same time, home-use devices have been introduced for a variety of indications. These devices are characterized by low power and special safety features aimed at preventing accidents, risks, and side effects. Despite the reduced efficacy of such self-treatment devices, there is an increased risk of misuse, given that the basic prerequisite for adequate treatment cannot be ensured, to wit, the exact diagnosis and therapeutic indication. Consequently, during hair removal or anti-wrinkle treatment, pigmented lesions and cutaneous neoplasms may be altered, thus giving rise to expected, unexpected and new side effects and complications. In the aforementioned setting, it is important that all potential users of these new technologies be properly trained in a manner that ensures those treated a maximum of safety and efficacy in accordance with the guiding principle "diagnosis certa - ullae therapiae fundamentum".

“…Ganz besonders wichtig ist die Vermeidung einer UV‐Belastung vor und mindestens 24 Stunden nach einer HBL‐Applikation. Schon die einmalige Applikation > 3 SED (Standard Erythema Dose) führte zu zahlreichen unerwünschten Effekten wie Erytheme (87 %), Purpura (27 %), Blasen (20 %), Ödeme (13 %), Krusten (13 %), Hyper‐ (60 %), und Hypopigmentation (20 %) . Eine immer wiederkehrende Fehlerquelle sind aufgrund phototoxischer Reaktionen und bulk heating Tattoos im Epilationsbereich.…”

Section: Epilationunclassified

Neue Laser und Strahlquellen – alte und neue Risiken?

Schwandt²,

Seeber³

et al. 2017

Self Cite

In diesem Szenario ist es wichtig, alle potenziellen Anwender dieser neuen Technologien vor deren Einsatz so zu qualifizieren, dass den Therapierten maximale Therapiesicherheit bei höchster Effizienz unter dem Leitbild diagnosis certa -ullae therapiae fundamentum garantiert wird. SummaryRecent developments (new wavelengths, treatment concepts, and combinations) in the field of lasers, intense pulsed light (IPL), LED, as well as new energy and light sources have opened up new therapeutic options that extend beyond mere aesthetic indications. Thus, while fractional lasers used to be employed to merely treat wrinkles, the same devices -in the context of laser-assisted drug delivery -have now become important tools in the treatment of scars, field cancerization, and epithelial tumors.