Side-Effects of Penicillin Treatment

Recent Difficulties in the Treatment of Gonorrhoea with Penicillin

“…In venereal diseases clinics fatalities have fortunately been very uncommon (Smith et al 1955;Morton 1957; Willcox and Fryers 1957;Brown 1960) and indeed WHO Surveys (Willcox 1958a) and o~her data have lent support to the commonly held view that they are very rare in relation to the vast amounts of penicillin manufactured, now measurable in millions of pounds avoirdupois annually _ (Guthe et al 1958).…”

Editorial

“…Allergic reactions of all sorts were more common in patients receiving multiple injections for syphilis than in patients given one injection for the treatment of gonorrhoea. Morton (1957) reported on 9,382 injections of penicillin given to 403 patients: with 5,870 injections of procaine penicillin given to 256 patients, there were nine instances of anaphy-lactic reaction, but with 3,512 injections of the longacting benethamine penicillin given to 147 patients, there was only one such case; all recovered.…”