Sideroxylon obtusifolium herbal medicine characterization using pyrolysis GC/MS, SEM and different thermoanalytical techniques

Correia, Lidiane Pinto; Santana, Cleildo P.; Medeiros, Francinalva Dantas; Macêdo, Rui Oliveira

doi:10.1007/s10973-015-4986-1

Cited by 13 publications

(6 citation statements)

References 12 publications

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“…The data demonstrate that mineral waste samples of leaves and fruits in different particle sizes can be used to indicate the integrity of the sample for each particle size differentiation. These results corroborate those found by Correia et al, 2016 [ 20 ].…”

Section: Resultssupporting

confidence: 93%

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Model Analytical Development for Physical, Chemical, and Biological Characterization ofMomordica charantiaVegetable Drug

Brandão

Guimarães

Santos³

et al. 2016

Journal of Analytical Methods in Chemistry

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Momordica charantia is a species cultivated throughout the world and widely used in folk medicine, and its medicinal benefits are well documented, especially its pharmacological properties, including antimicrobial activities. Analytical methods have been used to aid in the characterization of compounds derived from plant drug extracts and their products. This paper developed a methodological model to evaluate the integrity of the vegetable drug M. charantia in different particle sizes, using different analytical methods. M. charantia was collected in the semiarid region of Paraíba, Brazil. The herbal medicine raw material derived from the leaves and fruits in different particle sizes was analyzed using thermoanalytical techniques as thermogravimetry (TG) and differential thermal analysis (DTA), pyrolysis coupled to gas chromatography/mass spectrometry (PYR-GC/MS), and nuclear magnetic resonance (1H NMR), in addition to the determination of antimicrobial activity. The different particle surface area among the samples was differentiated by the techniques. DTA and TG were used for assessing thermal and kinetic parameters and PYR-GC/MS was used for degradation products chromatographic identification through the pyrograms. The infusions obtained from the fruit and leaves of Momordica charantia presented antimicrobial activity.

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Section: Resultssupporting

confidence: 93%

“…The first step of thermal decomposition is to hallmark the loss of volatile products, mainly free water, as this event occurs in fusion tracks and with vaporization of the substance [ 19 , 20 ]. These weight loss values are related to water, and the recommended level of water in the sample is less than 14% [ 21 ].…”

Section: Resultsmentioning

confidence: 99%

Model Analytical Development for Physical, Chemical, and Biological Characterization ofMomordica charantiaVegetable Drug

Brandão

Guimarães

Santos³

et al. 2016

Journal of Analytical Methods in Chemistry

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“…The thermogram of plant extract showed weight loss in different stages. In the first stage, there is a 9% weight loss up to 100 °C that can be attributed to free solvent and volatile products detachment [ 26 ]. In the second stage (100–130 °C), a weight loss of 15% observed may be due to the loss of bound solvent molecules and volatile products of the plant extract.…”

Section: Resultsmentioning

confidence: 99%

Biological Evaluation, Phytochemical Screening, and Fabrication of Indigofera linifolia Leaves Extract-Loaded Nanoparticles

et al. 2022

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Indigofera linifolia is a medicinally important plant, and by virtue of its rich phytochemical composition, this plant is widely used as essential component in traditional medication systems. Due to its wide range of medicinal applications, the extract-loaded chitosan (Ext+Ch), extract-loaded PEG (Ext+PEG), and extract-loaded locust bean gum (Ext+LGB) nanoparticles (NPs) were prepared in the present study. The prepared NPs were then evaluated for their antibacterial, antioxidant, and antidiabetic potentials. Antibacterial activities of the crude extract and the synthesized NPs were performed following standard procedures reported in the literature. The antioxidant capabilities of extract and NPs were evaluated using DPPH free radical scavenging assay. The antidiabetic potential of the samples was evaluated against α-amylase and α-glucosidase. Ext+PEG NPs showed more potent antibacterial activity against the selected strains of bacteria with the highest activity against Escherichia coli. The lowest antibacterial potential was observed for Ext+LGB NPs. The Ext+LGB NPs IC50 value of 39 μg/mL was found to be the most potent inhibitor of DPPH free radicals. Ext+LGB NPs showed a greater extent of inhibition against α-glucosidase and α-amylase with an IC50 of 83 and 78 μg/mL, whereas for the standard acarbose the IC50 values recorded against the mentioned enzymes were 69 and 74 μg/mL, respectively. A high concentration of phenolics and flavonoids in the crude extract was confirmed through TPC and TFC tests, HPLC profiling, and GC–MS analysis. It was considered that the observed antibacterial, antidiabetic, and antioxidant potential might be due the presence of these phenolics and flavonoids detected. The plant could thus be considered as a potential candidate to be used as a remedy of the mentioned health complications. However, further research in this regard is needed to isolate the exact responsible compounds of the observed biological potentials exhibited by the crude extract. Further, toxicity and pharmacological evaluations in animal models are also needed to establish the safety or toxicity profile of the plant.

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“…The milling of the raw plant material is a critical step in obtaining vegetal drugs, extracts, and herbal medicines, and therefore, granulometry powder control is an important step of the production process (Correia et al, 2016). Among the analyses performed to ensure vegetal drugs' quality are quantitative and qualitative analyses of purity, integrity, and active contents (USP, 2012).…”

Section: Introductionmentioning

confidence: 99%

Tacinga inamoena vegetal drug characterization using phytochemistry, pharmacopoeial methods and thermoanalytical techniques

Silva¹,

Reis²,

Santana³

et al. 2020

Braz. J. Pharm. Sci.

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Sideroxylon obtusifolium herbal medicine characterization using pyrolysis GC/MS, SEM and different thermoanalytical techniques

Cited by 13 publications

References 12 publications

Model Analytical Development for Physical, Chemical, and Biological Characterization ofMomordica charantiaVegetable Drug

Model Analytical Development for Physical, Chemical, and Biological Characterization ofMomordica charantiaVegetable Drug

Biological Evaluation, Phytochemical Screening, and Fabrication of Indigofera linifolia Leaves Extract-Loaded Nanoparticles

Tacinga inamoena vegetal drug characterization using phytochemistry, pharmacopoeial methods and thermoanalytical techniques

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