Sífilis e infección por el virus de la inmunodeficiencia humana: una endemia en hombres que tienen sexo con hombres

González-Domenech, Carmen M.; Martín-Portugués, I. Antequera; Clavijo-Frutos, Encarnación; Márquez‐Solero, Manuel; Santos-González, Jesús; Palacios-Muñoz, Rosario

doi:10.1016/j.eimc.2014.07.013

Cited by 15 publications

(2 citation statements)

References 9 publications

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“…One limitation to better understanding this disease is the high percentage of asymptomatic syphilis, according to González Domenech [ 31 ], and at least 35% of patients belong to this group. This is a major problem because the disease can be misdiagnosed or not even treated, and not all MSM may be attending their physician appointments and, therefore, do not even notice a problem.…”

Section: Resultsmentioning

confidence: 99%

IL-10 and IL-17 as Progression Markers of Syphilis in People Living with HIV: A Systematic Review

et al. 2022

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Much is known about the natural history of syphilis; however, less is known about the immune response against it, and even less is known about people living with HIV (PLWH). Due to the lack of an animal model to study host‒pathogen interactions, it remains unclear how the host eliminates the bacteria. Here, we attempt to elucidate the immune response against infection by summarizing all the reported data in a systematic review. We found that only seven papers included PLWH, and they did not accurately describe the immune response against Treponema pallidum since only lymphopenia was reported upon coinfection. On the other hand, at least sixteen papers described the host‒pathogen interaction in individual cell populations. Using this information, we established the kinetics of the immune response against syphilis and hypothesized how CD4+ T cells, such as Th17 and T rex cells, worsen the progression of the disease in PLWH through their hallmark cytokines, IL-10 and IL-17, and how these two cytokines may play important roles as biomarkers.

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Section: Resultsmentioning

confidence: 99%

IL-10 and IL-17 as Progression Markers of Syphilis in People Living with HIV: A Systematic Review

et al. 2022

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“…Por último, se considera pertinente enfatizar la relación de la sífilis con el vih/sida. Diversos estudios [28][29][30] reportan que existe una alta prevalencia de pacientes infectados con ambas patologías, de aproximadamente 40 a 50%; sin embargo, en el presente estudio solo el 10% de la población padecía de ambas. Aunque no hay coincidencia, no se le resta importancia a dicho dato, debido a que los pacientes diagnosticados con alguna de estas enfermedades deben recibir mayor educación para reducir el riesgo de una nueva infección.…”

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Lesiones bucales características de la sífilis encontradas en 3 servicios de estomatología de Latinoamérica

et al. 2017

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Cómo citar este artículo: Carmona M, Porto I, Ríos Y, Lanfranchi H. Lesiones bucales características de la sífilis, encontradas en tres servicios de estomatología de Latinoamérica. Rev Nac Odontol. 2018;13(26):1-8. doi: http://dx.doi.org/10. 16925/ od.v13i26.1788 Resumen Introducción: la sífilis es una enfermedad considerada como antigua, que ha causado grandes estragos durante toda la historia de la humanidad, y a pesar de métodos de protección sexual y antibióticos para combatir esta infección, en la actualidad todavía su prevalencia es preocupante. El odontólogo juega un papel imprescindible en este campo, debido a que debe ser capacitado para detectar las manifestaciones de la enfermedad en cavidad bucal de una forma temprana, con lo que se evitaría su progresión.Metodología: se realiza un estudio descriptivo de corte transversal, con veinte pacientes que consultaron tres servicios de estomatología de Suramérica; se les realiza examen estomatológico e historia clínica exhaustiva; se clasificaron las lesiones encontradas y se analizaron los demás datos recogidos.Resultados: la lesión prevalente en sífilis primaria fue la úlcera y solo se detectó un caso; acerca de la forma secundaria se detectaron diecinueve casos y se encontraron múltiples lesiones asociadas; por último, no se encontró ningún caso de sífilis terciaria.Conclusiones: se considera fundamental la divulgación de estos resultados y mayores investigaciones en este campo, con el fin de educar y así evitar la progresión de la sífilis a una forma latente o terciaria que ponga en riesgo la vida de la población.Palabras clave: enfermedades de transmisión sexual, neoplasias de la boca, serodiagnóstico de la sífilis, sífilis. AbstractIntroduction: Syphilis is an ancient disease that has caused great damage throughout the history of humanity and, despite sexual protection methods and antibiotics to combat this infection, its prevalence is still alarming today. The dentist plays an essential role in this field because he must be trained to early detect the manifestations of the disease in the oral cavity, which would prevent its progression. Materials and methods:A cross-sectional, descriptive study was conducted, with 20 patients who consulted three stomatology services in South America; a stomatological examination was done and an exhaustive clinical history was obtained; the lesions found were classified and the other data collected were analyzed.Results: The lesion prevalent in primary syphilis was ulcers and only one case was detected; about the secondary form, nineteen cases were detected, and multiple associated lesions were found; finally, no case of tertiary syphilis was found.Conclusions: Disclosure of these results and further research in this field are considered essential to educate and thus prevent the progression of syphilis to a latent or tertiary form that endangers the life of the population.

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Diagnosing acquired syphilis through oral lesions: the 12 year experience of an Oral Medicine Center

Matias

Jesus

Resende³

et al. 2020

Brazilian Journal of Otorhinolaryngology

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Sífilis e infección por el virus de la inmunodeficiencia humana: una endemia en hombres que tienen sexo con hombres

Cited by 15 publications

References 9 publications

IL-10 and IL-17 as Progression Markers of Syphilis in People Living with HIV: A Systematic Review

IL-10 and IL-17 as Progression Markers of Syphilis in People Living with HIV: A Systematic Review

Lesiones bucales características de la sífilis encontradas en 3 servicios de estomatología de Latinoamérica

Diagnosing acquired syphilis through oral lesions: the 12 year experience of an Oral Medicine Center

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