Signal-averaged electrocardiography and echocardiography in the evaluation of myocardial involvement in progressive systemic sclerosis

Paradiso, Michele; Gabrielli, Francesco; Coppotelli, L; G, Aguglia; Pergolini, Mario; Leonardo, M. Lima; Basili, Stefania; Alcini, E; Masala, C; Cordova, C

doi:10.1016/0167-5273(95)02521-9

Cited by 7 publications

(2 citation statements)

References 28 publications

(8 reference statements)

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“…Other frequent abnormal findings include late potentials by signal averaged electrocardiography, decreased heart rate variability (35), and greater QT dispersion (36). Using signal averaged electrocardiography, Paradiso et al reported that 46% of the scleroderma patients (vs. 8% of control subjects) possessed late ventricular potentials (37). Morelli et al noted an increase in late ventricular potentials in scleroderma patients (20%) who frequently had a septal infarct pattern on their electrocardiogram (38).…”

Section: Arrhythmias Related To Pah In Specific Subpopulations Of Pahmentioning

confidence: 99%

Arrhythmias in Pulmonary Arterial Hypertension

Rajdev

Garan

Biviano

2012

Progress in Cardiovascular Diseases

104

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Cardiac arrhythmias are important contributors to morbidity and mortality in patients with pulmonary arterial hypertension (PAH). Such patients manifest a substrate resulting from altered autonomics, repolarization abnormalities, and ischemia. Supraventricular arrhythmias such as atrial fibrillation and flutter are associated with worsened outcomes, and maintenance of sinus rhythm is a goal. Sudden death is a relatively common issue, though the contribution of malignant ventricular arrhythmias versus bradyarrhythmias differs from non-PAH patients. Congenital heart disease patients with PAH benefit from catheter ablation of medically refractory arrhythmias. Clinical studies of defibrillator/pacemaker therapy for primary prevention against sudden death in PAH patients are lacking.

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Section: Arrhythmias Related To Pah In Specific Subpopulations Of Pahmentioning

confidence: 99%

Arrhythmias in Pulmonary Arterial Hypertension

Rajdev

Garan

Biviano

2012

Progress in Cardiovascular Diseases

104

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“…Patchy myocardial fibrosis represents an ideal substrate for reentry tachyarrhythmias. LVPs occurred in patients with diffuse progressive systemic sclerosis; a lower myocardial involvement was noticed in the CREST syndrome (Paradiso et al, 1996). Diffuse abnormalities of the cardiac tissue detected by SAECG may be present in patients with systemic sclerosis without cardiac symptoms and higher skin scores correlated with the presence of LVPs (Paradiso et al, 2002).…”

Section: Connective Tissue and Systemic Diseasesmentioning

confidence: 99%