1997
DOI: 10.1016/s0002-9629(15)40229-0
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Signal Transduction: Activation of the Guanylate Cyclase-Cyclic Guanosine-3' -5' Monophosphate System by Hormones and Free Radicals

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Cited by 19 publications
(27 citation statements)
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“…This factor is regulated by the intracellular redox state [38]. The transduction-signaling cascade is sensitive to oxidants and antioxidants [39], including glutathione peroxidase and GSH, which are stimulated by melatonin [40,41].…”
Section: Discussionmentioning
confidence: 99%
“…This factor is regulated by the intracellular redox state [38]. The transduction-signaling cascade is sensitive to oxidants and antioxidants [39], including glutathione peroxidase and GSH, which are stimulated by melatonin [40,41].…”
Section: Discussionmentioning
confidence: 99%
“…The possibility that these anions, that are responsible for the remaining relaxation in the presence of L-NAME, may induce relaxation by activation of guanylate cyclase [35] was examined by using ODQ, an inhibitor of this enzyme [36]. The fact that the combination of L-NAME and ODQ resulted in the same degree of relaxation as L-NAME alone suggests that guanylate cyclase is not involved.…”
Section: Discussionmentioning
confidence: 99%
“…To assess further the nature of the action of E 2 , both aortic cGMP and cAMP contents were examined [40,41]. Increased basal aortic cGMP content, but not basal aortic cAMP content, were observed in E 2 -treated MSHR.…”
Section: Discussionmentioning
confidence: 99%