Signaling from maize organ primordia via FASCIATED EAR3 regulates stem cell proliferation and yield traits

Je, Byoung Il; Gruel, Jérémy; Lee, Young Koung; Bommert, Peter; Demesa-Arévalo, Edgar; Eveland, Andrea L.; Wu, Qingyu; Goldshmidt, Alexander; Meeley, Robert B.; Bartlett, Madelaine; Komatsu, Mai; Sakai, Hajime; Jönsson, Henrik; Jackson, David

doi:10.1038/ng.3567

Cited by 206 publications

(227 citation statements)

References 55 publications

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“…The non-cell-autonomous properties of ADT, the product of an enzyme encoded by the maize gene bladekiller1, which acts in the thiamine biosynthesis pathway, is important for maintaining meristem indeterminacy (Woodward et al, 2010). FASCIATED EAR3, a key regulator of stem cell proliferation in maize, responds to the FON2-LIKE CLE PROTEIN1 peptide signal produced in lateral organ primordia (Je et al, 2016). Our results are consistent with and reinforce the standing hypothesis in the research field on YABBY function (Goldshmidt et al, 2008;Stahle et al, 2009;Sarojam et al, 2010;Tanaka et al, 2012): The maize drl gene products act in or through pathways that function non-cell autonomously, which traverse boundary domains or peripheral layers of the primordium to regulate developmental programs at the shoot apex.…”

Section: Primordia-derived Activities Of Drl Genes Regulate Shoot Mermentioning

confidence: 99%

Maize YABBY Genes drooping leaf1 and drooping leaf2 Regulate Plant Architecture

et al. 2017

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Leaf architecture directly influences canopy structure, consequentially affecting yield. We discovered a maize (Zea mays) mutant with aberrant leaf architecture, which we named drooping leaf1 (drl1). Pleiotropic mutations in drl1 affect leaf length and width, leaf angle, and internode length and diameter. These phenotypes are enhanced by natural variation at the drl2 enhancer locus, including reduced expression of the drl2-Mo17 allele in the Mo17 inbred. A second drl2 allele, produced by transposon mutagenesis, interacted synergistically with drl1 mutants and reduced drl2 transcript levels. The drl genes are required for proper leaf patterning, development and cell proliferation of leaf support tissues, and for restricting auricle expansion at the midrib. The paralogous loci encode maize CRABS CLAW co-orthologs in the YABBY family of transcriptional regulators. The drl genes are coexpressed in incipient and emergent leaf primordia at the shoot apex, but not in the vegetative meristem or stem. Genome-wide association studies using maize NAM-RIL (nested association mapping-recombinant inbred line) populations indicated that the drl loci reside within quantitative trait locus regions for leaf angle, leaf width, and internode length and identified rare single nucleotide polymorphisms with large phenotypic effects for the latter two traits. This study demonstrates that drl genes control the development of key agronomic traits in maize.

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Section: Primordia-derived Activities Of Drl Genes Regulate Shoot Mermentioning

confidence: 99%

Maize YABBY Genes drooping leaf1 and drooping leaf2 Regulate Plant Architecture

et al. 2017

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“…A third maize CLE gene, ZmFCP1, is expressed in leaf primordia, similar to the rice ortholog that gave it its name. Zmfcp1 mutants also show a clv-like 'fasciated ear' phenotype, suggesting that this CLE peptide can regulate the SAM by signaling from differentiating cells (Je et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

“…ZmCLE7 is expressed in the ear inflorescence meristem, and it is overexpressed in the CLV-related mutant fasciated ear3 ( fea3) (Je et al, 2016). A third maize CLE gene, ZmFCP1, is expressed in leaf primordia, similar to the rice ortholog that gave it its name.…”

Section: Introductionmentioning

confidence: 99%

“…A CLV3 ortholog has not yet been functionally characterized in maize, but two candidates, Zea mays (Zm) CLE7 and ZmCLE14, were identified by phylogenetic analysis, and both peptides encoded by these genes were shown to have a negative effect on SAM size when applied exogenously (Je et al, 2016). ZmCLE7 is expressed in the ear inflorescence meristem, and it is overexpressed in the CLV-related mutant fasciated ear3 ( fea3) (Je et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

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CLAVATA-WUSCHEL signaling in the shoot meristem

2016

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Shoot meristems are maintained by pluripotent stem cells that are controlled by CLAVATA-WUSCHEL feedback signaling. This pathway, which coordinates stem cell proliferation with differentiation, was first identified in Arabidopsis, but appears to be conserved in diverse higher plant species. In this Review, we highlight the commonalities and differences between CLAVATA-WUSCHEL pathways in different species, with an emphasis on Arabidopsis, maize, rice and tomato. We focus on stem cell control in shoot meristems, but also briefly discuss the role of these signaling components in root meristems.

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“…The null fea3 mutant produces fasciated ears and increased KRN. In contrast, weak alleles of fea3 enhance yield traits (Je et al 2016).…”

Section: Manipulation Of Dosage Effect and Genome Editingmentioning

confidence: 99%

Revisiting Domestication to Revitalize Crop Improvement: The Florigen Revolution

Park

Lee

Kang

et al. 2016

Plant Breed. Biotech.

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Most flowering plants have evolved to coordinate proper floral transition in shoot apical meristems at an appropriate time during development, referred to as "flowering time." In domesticated crops, shoot life time has been manipulated to enhance productivity via synchronizing flowering time to the local environment, thereby creating a balance between vegetative and reproductive plant architecture during the year. Rice, a typical single transitional crop, has acquired balance between prolonged tiller growth and a relatively short reproductive phase on individual shoot, resulting in increasing yield. Crops with sympodial growth, such as tomato, which undergo multiple floral transitions on the main shoot, have been artificially selected for the determination of shoot growth by investigating the dosage sensitivity of florigen activation controlling flowering time on individual shoots. Here, we summarize recent genetic-molecular studies on tomato, which have been subject to genetic manipulation of flowering time in an effort to optimize seed productivity. We also review advanced genetic approaches as potential new tools for the enhancement of crop yield by manipulating flowering time via the dosage effect of florigen.

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Signaling from maize organ primordia via FASCIATED EAR3 regulates stem cell proliferation and yield traits

Cited by 206 publications

References 55 publications

Maize YABBY Genes drooping leaf1 and drooping leaf2 Regulate Plant Architecture

Maize YABBY Genes drooping leaf1 and drooping leaf2 Regulate Plant Architecture

CLAVATA-WUSCHEL signaling in the shoot meristem

Revisiting Domestication to Revitalize Crop Improvement: The Florigen Revolution

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