Signals in inferotemporal and perirhinal cortex suggest an untangling of visual target information

Pagan, Marino; Urban, Luke S; Wohl, Margot; Rust, Nicole C.

doi:10.1038/nn.3433

Cited by 122 publications

(152 citation statements)

References 43 publications

Supporting

Mentioning

143

Contrasting

Order By: Relevance

“…For the tuned-excitatory type, the models with the nonlinearity inserted after or before binocular combination have similar mathematical expressions [40,42]. Similar nonlinear mechanisms have been suggested for transparent-motion detection [43], contrast-invariant orientation tuning [44] and the construction of linearly separable representations of target versus distractor objects [45].…”

Section: Reversed Depth In Anti-correlated Random-dot Stereogramsmentioning

confidence: 57%

Weighted parallel contributions of binocular correlation and match signals to conscious perception of depth

Fujita

Doi

2016

Phil. Trans. R. Soc. B

View full text Add to dashboard Cite

One contribution of 15 to a theme issue 'Vision in our three-dimensional world'. Binocular disparity is detected in the primary visual cortex by a process similar to calculation of local cross-correlation between left and right retinal images. As a consequence, correlation-based neural signals convey information about false disparities as well as the true disparity. The false responses in the initial disparity detectors are eliminated at later stages in order to encode only disparities of the features correctly matched between the two eyes. For a simple stimulus configuration, a feed-forward nonlinear process can transform the correlation signal into the match signal. For human observers, depth judgement is determined by a weighted sum of the correlation and match signals rather than depending solely on the latter. The relative weight changes with spatial and temporal parameters of the stimuli, allowing adaptive recruitment of the two computations under different visual circumstances. A full transformation from correlation-based to match-based representation occurs at the neuronal population level in cortical area V4 and manifests in single-neuron responses of inferior temporal and posterior parietal cortices. Neurons in area V5/MT represent disparity in a manner intermediate between the correlation and match signals. We propose that the correlation and match signals in these areas contribute to depth perception in a weighted, parallel manner.This article is part of the themed issue 'Vision in our three-dimensional world'.

show abstract

Section: Reversed Depth In Anti-correlated Random-dot Stereogramsmentioning

confidence: 57%

Weighted parallel contributions of binocular correlation and match signals to conscious perception of depth

Fujita

Doi

2016

Phil. Trans. R. Soc. B

View full text Add to dashboard Cite

show abstract

“…For example, neuronal signals related to whether a visual stimulus is a target or nontarget are observed in V4 and other areas of the ventral visual pathway (Chelazzi et al, 2001; Pagan et al, 2013). A simple perceptual mechanism of criterion shifts could be to selectively control the gain of these signals for different spatial locations.…”

Section: Discussionmentioning

confidence: 99%

Neuronal Modulations in Visual Cortex Are Associated with Only One of Multiple Components of Attention

Luo

Maunsell

2015

Neuron

116

161

View full text Add to dashboard Cite

Neuronal signals related to visual attention are found in widespread brain regions, and these signals are generally assumed to participate in a common mechanism of attention. However, the behavioral effects of attention in detection can be separated into two distinct components: spatially selective shifts in either the criterion or sensitivity of the subject. Here we show that a paradigm used by many single-neuron studies of attention conflates behavioral changes in the subject’s criterion and sensitivity. Then, using a task designed to dissociate these two components, we found that multiple aspects of attention-related neuronal modulations in area V4 of monkey visual cortex corresponded to behavioral shifts in sensitivity but not criterion. This result suggests that separate components of attention are associated with signals in different brain regions, and that attention is not a unitary process in the brain but instead consists of distinct neurobiological mechanisms.

show abstract

“…The definition of trajectory tangling used here differs somewhat from the recently introduced definition of representational tangling 70 . Representations are tangled if the sets of states corresponding to two stimulus classes cannot be separated by a smooth ( e.g.…”

Section: Methodsmentioning

confidence: 99%

Motor Cortex Embeds Muscle-like Commands in an Untangled Population Response

Russo

Bittner

Perkins

et al. 2018

Neuron

285

399

View full text Add to dashboard Cite

Summary Primate motor cortex projects to spinal interneurons and motor neurons, suggesting that motor cortex activity may be dominated by muscle-like commands. Extensive observations during reaching lend support to this view, but evidence remains ambiguous and much-debated. To provide a different perspective, we employed a novel behavioral paradigm that affords extensive comparison between time-evolving neural and muscle activity. We found that single motor cortex neurons displayed many muscle-like properties, but the structure of population activity was not muscle-like. Unlike muscle activity, neural activity was structured to avoid ‘tangling’: moments where similar activity patterns led to dissimilar future patterns. Avoidance of tangling was present across tasks and species. Network models revealed a potential reason for this consistent feature: low tangling confers noise robustness. Finally, we were able to predict motor cortex activity from muscle activity alone, by leveraging the hypothesis that muscle-like commands are embedded in additional structure that yields low tangling.

show abstract

Signals in inferotemporal and perirhinal cortex suggest an untangling of visual target information

Cited by 122 publications

References 43 publications

Weighted parallel contributions of binocular correlation and match signals to conscious perception of depth

Weighted parallel contributions of binocular correlation and match signals to conscious perception of depth

Neuronal Modulations in Visual Cortex Are Associated with Only One of Multiple Components of Attention

Motor Cortex Embeds Muscle-like Commands in an Untangled Population Response

Contact Info

Product

Resources

About