Significance and Distribution of the Mic a/B Alleles Among the Worldwide Populations

Abstract

The Major histocompatibility complex chain 1(MIC) genes are recently studied upon their association with various infections, Autommune and Inflammatory diseases, various cancers and Graft rejections. The expression of these genes mediates numerous key cellular and immunological pathways. Numerous alleles are reported for these genes across the worldwide populations. This report utilizes the public domain data in effectively analyzing the various MIC allelic distributions in different population subgroups in the light of previous reports and established hypotheses in the context of clinical and population genetics.