Significance of arterial stiffness in Tridosha analysis: A pilot study

Kumar, P. Venkata Giri; Deshpande, Sudheer; Joshi, Aniruddha; More, Pooja; Nagendra, H R

doi:10.1016/j.jaim.2017.02.012

Cited by 6 publications

(2 citation statements)

References 16 publications

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“…Cyclodextrins, mostly α-cyclodextrin, are found to form complexes with the dietary fat which are stable enough to undergo enzymatic hydrolysis by lipase. This restrains accumulation of fat in human body 21 , 22 . Hence, inclusion complex of SNP and cyclodextrins can be of a great deal for the weight loss/weight management dietary food supplement for sportsman or obese person 23 .…”

Section: Introductionmentioning

confidence: 99%

Study to Probe Subsistence of Host-Guest Inclusion Complexes of α and β-Cyclodextrins with Biologically Potent Drugs for Safety Regulatory Dischargement

Rajbanshi

Saha

Das

et al. 2018

Sci Rep

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Host-guest interaction of two significant drugs, phenylephrine hydrochloride and synephrine with α and β-cyclodextrins were studied systematically. Initially two simple but reliable physicochemical techniques namely conductance and surface tension were employed to find out saturation concentration for the inclusion and its stoichiometry. The obtained 1:1 stoichiometry was further confirmed by two spectrometric methods, UV-Vis study and spectrofluorimetry. Significant shifts in IR stretching frequency also support the inclusion process. Relative stabilities of the inclusion complexes were established by the association constants obtained from UV-Vis spectroscopic measurements, program based mathematical calculation of conductivity data. Calculations of the thermodynamic parameters dictates thermodynamic feasibility of the inclusion process. Spectrofluorometric measurement scaffolds the UV-Vis spectroscopic measurement validating stability of the ICs once again. Mass spectroscopic measurement gives the molecular ion peaks corresponding to the inclusion complex of 1:1 molar ratio of host and guest molecules. The mechanism of inclusion was drawn by 1H-NMR and 2D ROESY spectroscopic analysis. Surface texture of the inclusion complexes was studied by SEM. Finally, the cytotoxic activities of the inclusion complexes were analyzed and found, Cell viability also balances for non-toxic behavior of the ICs. Moreover, all the studies reveal the formation of inclusion complexes of two ephedra free, alternatively emerging drugs (after their banned product having ephedra) SNP, PEH with α and β-CD which enriches the drug delivery system with their regulatory release without any chemical modification.

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Section: Introductionmentioning

confidence: 99%

Study to Probe Subsistence of Host-Guest Inclusion Complexes of α and β-Cyclodextrins with Biologically Potent Drugs for Safety Regulatory Dischargement

Rajbanshi

Saha

Das

et al. 2018

Sci Rep

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“…The stiffness indices are computes as follows: 25 Stiffness index (SI)=height of the person/(T4-T1), Reflection index (RI)=diastolic peak/systolic peak (P4/P1) and fullness Index (FI)=(P3/P1).…”

Section: Pulse Parametersmentioning

confidence: 99%

Nadifit: a novel single position pulse based diagnostic system

Y. C.,

B.,

Y. C.

2023

Int J Community Med Public Health

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Both traditional Chinese medicine (TCM) and traditional ayurvedic medicine (TAM) rely on a system of radial pulse diagnostics to assess a patient's health. The doctor or practitioner should place all three fingers on the patient's wrist and feel the styloid processes to detect any changes in the radial pulse. However, finding medical professionals skilled in pulse diagnosis or nadipariksha is becoming increasingly challenging in the current and upcoming generation. One technological approach that could solve this issue once and for all would be to transform objective pulse diagnosis into a subjective process. To automate this procedure, however, three separate sensors must be constructed for three positions in order to capture pulse at varying pulse pressures, which increases the hardware complexity for consumer use. To simplify the process and ensure a correct diagnosis, this study presents an effort to create the smart portable system Nadifit, which takes a single pulse reading from the patient. A single pulse is all that's needed to identify distinctive organ patterns, which can then be analyzed to provide insight into potential health issues. Analogue signals are quantified with the help of a microphone, a transmitter, and a 32-bit microprocessor. The data is acquired with a precision of 10 bits and virtually no electronic or contaminating noise outside of the system. The computer receives the collected pulse signal and does time and frequency domain analysis of the Nadi patterns, shapes, and width to determine the presence of the three ayurveda doshas (Vata, pitta, and kapha) as well as Chinese organ patterns (such as Qi stagnation, yin deficiency, yang excess, etc.). The experimental results demonstrate the effectiveness of the suggested system in identifying dosha, making it highly tailored to the individual patient's health issue. It is also demonstrated that the pulse waveform demonstrates the desired fluctuations in relation to patient age, pressure applied to the sensing element and full vs. empty stomach. Comparisons of stiffness across age groups are also performed. Practitioners, vaidhyas, and medical professionals are used to verify the system's accuracy. Hence, we believe a larger segment of the general public will be able to make use of our technology.

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Constitution and pathology

Al-Shura

2020

Perspectives of Ayurveda in Integrative Cardiovascular Chinese Medicine for Patient Compliance

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Significance of arterial stiffness in Tridosha analysis: A pilot study

Cited by 6 publications

References 16 publications

Study to Probe Subsistence of Host-Guest Inclusion Complexes of α and β-Cyclodextrins with Biologically Potent Drugs for Safety Regulatory Dischargement

Study to Probe Subsistence of Host-Guest Inclusion Complexes of α and β-Cyclodextrins with Biologically Potent Drugs for Safety Regulatory Dischargement

Nadifit: a novel single position pulse based diagnostic system

Constitution and pathology

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