Significance of biochemical markers of myocardial injury in patients with acute myocardial infarction and COVID-19

Abstract

Clinical and instrumental data of patients with acute myocardial infarction are of little informative value for COVID-19 identification. The aim is to study the significance of myocardial injury markers on admission in patients with acute myocardial infarction on COVID-19 background. At admission to the hospital in 20 patients with acute myocardial infarction and COVID-19 in blood markers of myocardial damage (highly sensitive troponin T, myoglobin and creatine kinase MB fraction) were studied using immunochemiluminescent method on immunoenzyme analyzer “Cobas e 411” (“Roche Diagnostics”, Germany). The values of highly sensitive troponin T in patients with acute myocardial infarction and COVID-19 were significantly lower than in patients with acute myocardial infarction without COVID-19 (94.8 vs. 171.8 pg/ml). There were no statistically significant differences in the values of myoglobin and the MB creatine kinase fraction in the study groups. Thus, markers of myocardial damage in patients with acute myocardial infarction have no predictive value in relation to COVID-19.