Significance of duodenal mucosal lesions: can they be a clue to a systemic disease?

Lee, Seung Woo

doi:10.3904/kjim.2017.282

Cited by 2 publications

(1 citation statement)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It has been reported that the prevalence and incidence of celiac disease in Korea is extremely rare (Table 1 ), with the hypothesis that the prevalence of at‐risk patients with a genetic predisposition (HLA‐DQ2/DQ8) is low and a relatively low intake of foods containing gluten, which may lead physicians to overlook celiac disease during routine clinical practice and medical training. 6 , 7 , 8 , 9 , 10 , 11 , 12 However, another important factor for the prevalence and incidence of celiac disease in Korea is the applicability of serologic assays to discover patients. In Korea, assays performed in overseas laboratories are not reimbursed by the single government payer and require out‐of‐pocket payment.…”

Section: Discussionmentioning

confidence: 99%

Underutilization of diagnostic assays for celiac disease in Korea

Choi

Lee

2021

Clinical Laboratory Analysis

View full text Add to dashboard Cite

Background Test utilization for the diagnosis of celiac disease may affect the prevalence and incidence of the disease in Korea. We aimed to investigate the test utilization of serological biomarkers for celiac disease in Korea. Methods We retrospectively investigated the test utilization of tissue transglutaminase IgA, gliadin IgA and IgG, and endomysial IgA antibody (Ab) assays between January 2011 and June 2020. Results During a nine‐year‐and‐six‐month study period, overall 307,322,606 clinical tests were requested from different clinical settings, such as local clinics, hospitals, university hospitals, and tertiary medical centers. Among them, only 58 tissue transglutaminase IgA, 22 gliadin IgA, 12 gliadin IgG, and 16 endomysial IgA Ab tests were performed on 79 Korean patients. Among them, one patient had positive transglutaminase IgA Ab result (1.3%). Conclusion Low prevalence and incidence of celiac disease in Korea may be due to an underutilization of diagnostic assays.

show abstract