Chemically reacting magnetohydrodynamic radiative flow of convective free stream nanofluid through a stretching cylinder using Buongiorno's model is discussed. The behavior of Brownian motion and thermophoresis is also appropriate. By adopting the similarity transformation, the partial differential equation is diminished into a first‐order ordinary differential equation (ODE). Since transformed equations are highly nonlinear these ODEs are solved by using mathematical simulation. The shooting procedure has been adopted to resolve converted equations along the attendant Runge–Kutta–Fehlberg technique. The reason behind the present work is to research the effects of different parameters of fluid, namely, magnetic parameter, free stream velocity, Brownian motion, thermophoresis, chemical reaction, heat radiation, Lewis number on nanoparticle concentration, temperature, and velocity distribution. The impact of significantly participating parameters on velocity, concentration, and temperature distribution is distinguished with appropriate physical significance. The convergence of solutions for temperature, velocity, and concentration profiles is studied carefully. The measured challenges of nanofluids are scale‐up capacity, increase in nanofluid viscosity, nanoparticle dispersion, and nanofluid cost. It is observed that nanoparticle temperature rises for more value of Brownian motion parameter while it declines for higher Lewis number. The current study in the cylindrical region is related to novel free stream flow in the presence of chemical reactions along with convective conditions which find applications in electronic systems like microprocessors and in a wide variety of industries and in the field of biotechnology. The current research helps control the transport phenomena, helping production companies to find the quality of the desired product.